September 2020 in “Annals of the National Academy of Medical Sciences. India” This article discusses the impact of COVID-19 on skin health, highlighting various cutaneous manifestations and the need for dermatologists to adapt their practices during the pandemic, but it reports no new results.
31 citations
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July 2017 in “Clinical Science” This review discusses the role of microRNAs in skin function and potential therapeutic applications, emphasizing their importance in wound healing and disease management, though it reports no new experimental findings.
22 citations
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September 2019 in “ACS omega” This study found that AGO@HPC nanocomposite films demonstrated enhanced mechanical, anti-ultraviolet, and antibacterial properties, suggesting potential for use in antibacterial packaging and wound-dressing applications.
14 citations
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January 1985 in “International Journal of Dermatology” The cause of alopecia areata was unknown, and while various treatments existed, no best treatment was agreed upon.
3 citations
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January 2020 in “Plastic and Aesthetic Research” This review discusses the fundamental hallmarks of aging as they relate to skin aging and highlights the prominent roles of oxidative damage and the extracellular matrix in photoaging, reporting no new results.
In this study, the researchers developed a biomimetic multilayer composite scaffold combining a decellularized amniotic membrane, fibroblast-laden collagen gel, and epidermal stem cells, which healed full-thickness skin wounds more quickly and effectively by regenerating hair follicles without scarring compared to Moropicin ointment.
December 2024 in “International Journal of Health Sciences and Research” This study describes the case of a 22-year-old female with alopecia areata linked to vitamin D deficiency, highlighting the importance of early diagnosis and management of deficiency to prevent broader health issues.
225 citations
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April 2018 in “Journal of Investigative Dermatology” Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
7 citations
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December 2024 in “Antibiotics” This review discusses the potential of cathelicidins in treating skin conditions but highlights significant challenges, including unclear clinical efficacy, safety concerns, and bacterial resistance, that must be addressed for successful medical application.
119 citations
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December 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, transcutaneously applied nanoparticles and viral vectors were shown to penetrate murine hair follicles, internalize in antigen-presenting cells, and induce immune responses, suggesting a promising approach for vaccine delivery.
1 citations
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June 2021 in “Journal of dermatology and dermatitis” This review explores the promising but varied effectiveness of tyrosine kinase inhibitors for treating different skin diseases, indicating their potential in dermatology while acknowledging the need for more evidence.
Nutrition plays a key role in managing skin disorders, with specific dietary changes helping improve conditions like acne, dermatitis, psoriasis, alopecia, and skin cancer.
24 citations
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January 2018 in “Development” This study found that Frizzled genes Fzd3 and Fzd6 are redundantly involved in controlling hair follicle polarity in mice, but operate through distinct mechanisms, highlighting their complex role in hair orientation.
22 citations
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April 2021 in “Human Cell” MicroRNAs may help diagnose and treat hair loss disorders.
9 citations
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July 2020 in “Experimental Dermatology” This review emphasizes the potential of repurposing topical L-thyroxine for skin ulcers and telogen effluvium and highlights the need for further exploration of its use in dermatology.
5 citations
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December 2005 in “Clinical Techniques in Equine Practice” This review discusses how skin lesions and haircoat changes in adult horses can indicate systemic diseases, emphasizing the need for veterinary evaluation, and reports no new clinical findings.
2 citations
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August 2022 in “Animals” This review discusses the potential use of essential oils and melatonin as nutraceuticals in dogs, highlighting their promising applications for addressing conditions like stress, anxiety, sleep disorders, and alopecia.
1 citations
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August 2025 in “Frontiers in Bioengineering and Biotechnology” This study found that a 3D wound model, the 3DWoundSE, showed improved responsiveness to injury and cytotoxic stimuli compared to an intact 3D skin equivalent, offering a reproducible and ethical alternative to animal models for early wound response assessment in dermatological research and drug development.
1 citations
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January 2023 in “Burns and trauma” This study found that tdDPC-EVs significantly improved wound healing by enhancing angiogenesis through the KLF4/VEGFA axis, offering advantages over traditional DPC-EVs.
1 citations
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February 2016 in “Cell Transplantation” In this study, researchers found that hair follicles and dermal fibroblasts, including dermal papilla cells, supported sustained hair growth in transplanted murine models, with RNA-seq analysis revealing active signaling pathways and gene expression patterns.
July 2025 in “International Journal of Pharmaceutical Sciences Review and Research” This review investigates how selenium, a trace element found in wheat, may impact hair health by examining its biochemical role in hair follicle biology and its potential therapeutic and toxicological effects.
February 2025 in “Stem Cell Research & Therapy” This study reviews advancements in hair follicle regeneration, discussing the benefits and limitations of methods such as organ germ assembling, stem cell induction, and bioprinting, while highlighting the challenges of replicating embryonic signals and finding suitable cell sources for clinical applications.
In this narrative review, the authors explored various rehabilitative techniques, including injections and physical therapies, that may enhance aesthetics and psychosocial wellbeing in patients with disabilities, emphasizing a multidisciplinary approach to improve both functional and cosmetic outcomes.
November 2023 in “Biomolecules” In this study involving genetically modified rats, researchers observed that specific mutations in the vitamin D receptor affect calcium levels and bone formation, emphasizing the receptor's role in maintaining healthy bone density and its importance in regulating hair cycle and skin health.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study provides evidence that innate lymphoid cells-type 1 can induce alopecia areata in human hair follicles, challenging the view that it is solely a CD8+ T cell-driven autoimmune disease.
April 2017 in “Journal of Investigative Dermatology” This study found that miR-486 and miR-451 levels were reduced in alopecia areata-affected skin, and delivering their mimics to mice mitigated symptoms by reducing inflammation and immune activity.
January 2013 in “Open journal of gastroenterology” This case report describes a patient with ulcerative colitis who also presented with an atypical clinical aspect of lichen ruber planus, vitiligo, and alopecia areata.
January 2024 in “Biomaterials Research” This study found that human hair follicle dermal papilla cells cultivated as 3D spheroids in hexanoyl glycol chitosan-coated dishes formed hair-like structures, with minoxidil enhancing growth, and successfully integrated into artificial skin models, suggesting advancements for hair loss treatments and skin restoration therapies.
1 citations
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July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
159 citations
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November 2007 in “American Journal of Pathology” In this study, researchers found that substance P triggered premature catagen development and immune changes in human scalp hair follicles, providing a possible biological link between stress and hair loss conditions like telogen effluvium and alopecia areata.