When the Skin Meets the Bowel: A Case Study

    January 2013 in “ Open journal of gastroenterology
    G. Giannotti, Anna Campanati, Di Sario Antonio, Corrado Rubini, Antonio Zizzi, Giuseppe Tarantino, Antonio Benedetti, Annamaria Offidani
    TLDR Ulcerative colitis can cause skin issues due to immune system problems.
    The document described a case of a patient with ulcerative colitis (UC), a chronic inflammatory disease of the colorectal region, who also exhibited extraintestinal manifestations including cutaneous involvement. The patient had an atypical presentation of lichen ruber planus and was also affected by vitiligo and alopecia areata. The authors suggested that immune dysregulation, leading to a lymphocyte-mediated destructive process, might be the pathogenetic link between the gut and skin-related manifestations.
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