30 citations
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October 2016 in “Current research in translational medicine” This essay reviews the role of human scalp hair follicles in the "brain-skin connection," highlighting their dual function as targets and sources of neurohormones, without reporting new experimental results.
January 2020 in “Turkish Journal of Dermatology” This review discusses the role of the CRH–ACTH–cortisol axis in skin function and its potential link to stress-related skin and hair conditions, and reports no new experimental results.
September 2024 in “Journal of the American Academy of Dermatology” Seborrheic dermatitis affects quality of life and sleep, linked to stress and nervous system changes.
10 citations
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November 2024 in “Nature Reviews Cardiology” Skin conditions can signal heart issues, highlighting the need for integrated care.
December 2024 in “Nutrients” In this review, skin changes like hair loss and brittle nails linked to nutritional deficiencies common in eating disorders are examined as critical diagnostic tools, highlighting the need for integrated care involving dermatologists, psychiatrists, and nutritionists for effective management.
293 citations
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November 2005 in “Trends in Immunology” This study indicates that stress in mice recruits specific neuroimmunoendocrine elements, leading to neurogenic skin inflammation that inhibits hair growth and highlights the skin's role in stress response research.
49 citations
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December 2009 in “Journal of Investigative Dermatology” This review explores the complex relationship between thyroid hormones and skin, discussing potential mechanisms and known interactions but reports no new clinical results, emphasizing the need for further research.
February 2024 in “International journal of molecular sciences” This study reviews current evidence on the role of ILC3s in the skin, highlighting their potential involvement in responding to microbiome changes such as those associated with acne and suggesting gaps in understanding their mechanisms.
4 citations
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June 2019 in “International Journal of Dermatology and Venereology” This review discusses the link between metabolic syndrome and various inflammatory skin diseases and reports no new clinical results, emphasizing the importance of recognizing skin manifestations as early indicators of systemic metabolic disorders.
66 citations
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July 2007 in “Journal of Molecular Medicine” This study in mice demonstrated that stress or nerve growth factor injection increases sensory neuron activity related to skin innervation, suggesting a strong connection between stress perception and neurogenic skin inflammation.
69 citations
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August 1995 in “Annals of Plastic Surgery” This study showed that ultrapulse carbon dioxide laser ablation can precisely remove rabbit skin without scarring, facilitating normal skin and hair restoration within one month.
7 citations
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January 2002 in “PubMed” This study observed significant skin changes, including epidermal thickening and pleomorphic keratinocytes, in rats after subchronic UVB irradiation, highlighting specific reactions in the dorsal skin.
1 citations
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March 2019 in “Hygiene and Sanitation” This study observed that exposure to heavy metal salts affected skin and hair morphology in mice, with lead acetate decreasing keratinocyte proliferation and zinc sulfate and sodium dichromate increasing it.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” This study identified key trends and influential contributors in skin microbiome research from the past decade, highlighting the growing publication rates, major players like the USA, and prominent researchers such as Gallo RL.
January 2024 in “Medical Research Archives” This source highlights the emerging field of psychodermatology, which examines the interplay between psychological factors and skin disorders, noting a historical lack of attention due to inadequate professional training and emphasizing the need for integrated care involving dermatologists, psychiatrists, and psychologists.
Nutrition plays a key role in managing skin disorders, with specific dietary changes helping improve conditions like acne, dermatitis, psoriasis, alopecia, and skin cancer.
7 citations
,
February 2018 in “Journal of Investigative Dermatology” This study investigates the role of peroxisome proliferator-activated receptor gamma in hair follicle morphogenesis using a novel mouse model but reports no new results, highlighting the need for further research on its function during the hair cycle.
2 citations
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January 2018 in “Elsevier eBooks” This review discusses the complex mechanisms behind acne vulgaris and suggests that dietary modification, along with pro- and prebiotics, may influence its pathogenesis by addressing stress-induced skin inflammation.
June 2019 in “Kufa journal for veterinary medical sciences” This study found that vitamin C deficiency in neonatal dairy calves is closely associated with skin problems like dermatosis, but treatment with vitamin C led to improvements.
October 1940 in “Clinical and Experimental Optometry” In this study, adult albino rats on a vitamin A deficient diet developed ocular symptoms like xerophthalmia and photophobia within four weeks, without showing loss of dark adaptation.
July 2023 in “Clinical, cosmetic and investigational dermatology” In this study, reflectance confocal microscopy was used to diagnose periorificial dermatitis, revealing specific skin changes such as hair follicle dilatation, increased vascular density, and inflammation, which help distinguish it from similar conditions.
22 citations
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November 2007 in “Journal of Investigative Dermatology Symposium Proceedings” This presentation reviews recent discoveries about signaling mechanisms in hair follicles and their potential influence on hair cycle control and melanogenesis, without presenting new experimental results.
3 citations
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September 2025 in “Frontiers in Microbiology” This review article proposes a possible skin-gut-fibrosis axis, suggesting that gut microbial metabolites may influence the development of keloids and hypertrophic scars by affecting immune responses and fibrotic signaling pathways, although direct evidence in skin fibrosis remains limited.
32 citations
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March 2021 in “Journal of endocrinological investigation” This review covers the connection between thyroid diseases and skin conditions like alopecia, dermatitis, and vitiligo, and highlights the need for further research on the role of thyroid hormones in skin health.
2 citations
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February 2024 in “International journal of molecular sciences” This review explores the connection between the gut-skin axis and the development of dermatological conditions like atopic dermatitis, psoriasis, alopecia areata, and acne, and discusses the potential of probiotics in reshaping the microbiome to alleviate these skin issues.
375 citations
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July 2006 in “Journal of Investigative Dermatology” This review discusses the brain-skin connection, the skin's role in stress response, and highlights unmet challenges in understanding stress-induced skin inflammation but reports no new experimental findings.
8 citations
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October 2023 in “Frontiers in Immunology” This study explores the potential connection between circulating cytokines and immune skin diseases, offering insights that may enhance understanding of their causes, diagnosis, and treatment approaches.
14 citations
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July 2019 in “Journal of Investigative Dermatology” In this study, targeted inactivation of the integrin-linked kinase gene in melanoblasts led to defects in cell migration, proliferation, and ability to populate the skin, implicating an integrin-linked kinase-Rac1 connection in melanocyte function.
5 citations
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December 1978 in “PubMed” This article reviews the connection between malabsorption syndrome and skin diseases, reporting common skin complications and noting their improvement with malabsorption treatment; it offers no new clinical results.
April 2026 in “Metabolites” This narrative review explores the strong association between various chronic inflammatory skin diseases and metabolic syndrome, emphasizing shared inflammatory pathways and chemokine involvement, though the precise molecular connections remain partially understood.