Acquired Epidermodysplasia Verruciformis in a Heart Transplant Patient

The document reports on a case of acquired epidermodysplasia verruciformis in a 63-year-old male heart transplant patient who was on immunosuppressive therapy with tacrolimus. The patient had a history of significant dermatoheliosis and a recent removal of squamous cell carcinoma on his cheek. He presented with a rash on his trunk and extremities and a hyperkeratotic nodule on his upper abdomen. Biopsies of the rash and nodule showed characteristic histologic findings of epidermodysplasia verruciformis, but no evidence of malignancy. Based on the patient's history and biopsy findings, a diagnosis of transplant-related epidermodysplasia verruciformis was made. No commercial support was identified for this study.