research Early Stage Alopecia Areata Is Associated With Inflammation in the Upper Dermis and Damage to the Hair Follicle Infundibulum
Early stage bald spots are linked to skin inflammation and damage to the upper part of the hair follicle.
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research Angiogenin Is Expressed in Human Dermal Papilla Cells and Stimulates Hair Growth
Angiogenin helps hair grow by stimulating cell growth and blood vessel formation.
research Human Papillomavirus E6/E7 Oncogenes Promote Mouse Ear Regeneration by Increasing the Rate of Wound Re-Epithelization and Epidermal Growth
HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.
research Sustained Human Hair Follicle Growth Ex Vivo in a Glycosaminoglycan Hydrogel Matrix
Human hair grows better in a special gel that mimics skin.
research Human Keratinocytes Derived from the Bulge Region of Hair Follicles Are Refractory to Differentiation
Hair follicle cells resist turning into skin cells.
research Stabilization of Epithelial Beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis
Keeping β-catenin levels high in mammary cells disrupts their development and branching.
research Basal Cells in the Epidermis and Epidermal Differentiation
The exact identity of skin stem cells and how skin cells differentiate is not fully known.
research Bead-Jet Printing Enabled Sparse Mesenchymal Stem Cell Patterning Augments Skeletal Muscle and Hair Follicle Regeneration
Bead-jet printing of stem cells improves muscle and hair regeneration.
research The Role of PPARγ-Mediated Signalling in Skin Biology and Pathology: New Targets and Opportunities for Clinical Dermatology
PPARγ is crucial for skin health but can have both beneficial and harmful effects.
research Characterization of Mouse Profilaggrin: Evidence for Nuclear Engulfment and Translocation of the Profilaggrin B-Domain During Epidermal Differentiation
Mouse profilaggrin helps in skin cell differentiation and may be involved in calcium signaling.
research An Advanced Review: Polyurethane-Related Dressings for Skin Wound Repair
Polyurethane dressings show promise for wound healing but need improvements to adapt better to the healing process.
research M-CSF-Stimulated Myeloid Cells Can Convert Into Epithelial Cells to Participate in Re-Epithelialization and Hair Follicle Regeneration During Skin Wound Healing
Myeloid cells can turn into skin and hair cells to help heal wounds.
research Significance of the S100A4 Protein in Psoriasis
The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
research Hair Follicle Stem Cells: In Vitro and In Vivo Neural Differentiation
Hair follicle stem cells can become different cell types and may help treat neurodegenerative disorders.
research Cutaneous Lymphadenoma Is a Distinct Trichoblastoma-like Lymphoepithelial Tumor With Diffuse Androgen Receptor Immunoreactivity, Notch1 Ligand in Reed-Sternberg-like Cells, and Common EGFR Somatic Mutations
Cutaneous Lymphadenoma is a unique skin tumor with specific protein markers and common gene mutations that may cause continuous cell growth.
research Condylomata Acuminata of HIV-Positive Men May Harbor Focal Areas of Dysplasia: Relevant Implications for the Management of Human Papillomavirus-Induced Disease in High-Risk Patients
Warts in HIV-positive men can have serious abnormal cell growth, needing careful analysis and treatment to prevent cancer.
research Single-Cell Transcriptome Sequence Profiling on the Morphogenesis of Secondary Hair Follicles in Ordos Fine-Wool Sheep
The research identifies genes linked to wool quality in sheep and provides insights to improve wool production.
research Comprehensive Analysis of the Circular RNA Expression Profile and CircRNA–miRNA–mRNA Network in the Goat Skin with Divergent Wool Curvature
Certain circular RNAs are crucial for wool growth and curvature in goats.
research Epidermal Stem Cells: Practical Perspectives and Potential Uses
Epidermal stem cells could lead to new treatments for skin and hair disorders.
research Comparison of the Therapeutic Effect of Allogeneic and Xenogeneic Small Extracellular Vesicles in Soft Tissue Repair
Both human and animal-derived small extracellular vesicles speed up skin healing equally well.
research Physiological Doses of Red Light Induce IL-4 Release in Cocultures Between Human Keratinocytes and Immune Cells
Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.
research Stem Cell Secretome as a Mechanism for Restoring Hair Loss Due to Stress, Particularly Alopecia Areata: Narrative Review
Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.
research Scaffolds for Epithelial and Hair Follicle Regeneration
Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
research Investigation of the Molecular Identity of the Junctional Zone in Human Skin
GATA6 is important for maintaining and differentiating cells in a key area of human skin.
research A Matter of Life and Death: Self-Renewal in Stem Cells
Stem cell self-renewal is complex and needs more research for full understanding.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research MoS2 Nanoclusters-Based Biomaterials for Disease-Impaired Wound Therapy
The SA-MS hydrogel is a promising material for improving wound healing and skin regeneration in diseases like diabetes and skin cancer.
research Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures
The method increases stem-like cells for better skin regeneration.
research Human Epidermal Neural Crest Stem Cells as Candidates for Cell-Based Therapies, Disease Modeling, and Drug Discovery
Human epidermal neural crest stem cells could be used for therapies, drug discovery, and disease modeling.
research sPLA2-IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation
Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.