12 citations,
May 2015 in “Molecular Medicine Reports” Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
106 citations,
October 2016 in “Cell Stem Cell” PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.
34 citations,
June 2008 in “In vitro cellular & developmental biology. Animal” Scientists created a long-lasting stem cell line from human hair that can turn into different skin and hair cell types.
144 citations,
September 2012 in “Genes & development” Aging causes skin stem cells to work less effectively.
42 citations,
May 2016 in “Annual Review of Cell and Developmental Biology” Fat cells are important for tissue repair and stem cell support in various body parts.
26 citations,
July 2012 in “Biochimica et Biophysica Acta (BBA) - General Subjects” The review found that different stem cell types in the skin are crucial for repair and could help treat skin diseases and cancer.
22 citations,
June 2013 in “International journal of molecular sciences” Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.
January 2024 in “Journal of tissue engineering” Sunlight exposure damages hair follicles, but certain stem cell-derived particles can reduce this damage and help with hair regeneration.
10 citations,
January 2013 in “Stem Cells and Development” Scientists identified a unique type of human skin stem cell that could help with tissue repair.
4 citations,
January 2013 in “Advances in Experimental Medicine and Biology” Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
Moles may stop growing due to cell cooperation, not just because of individual cell aging.
124 citations,
June 2020 in “Cell Stem Cell” Fat cells in the skin help start healing and form important repair cells after injury.
77 citations,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
9 citations,
March 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The symposium concluded that understanding the molecular mechanisms of skin aging could lead to better clinical practices and treatments.
6 citations,
January 2017 in “Advances in Experimental Medicine and Biology” Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
May 2013 in “Springer eBooks” Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.
22 citations,
March 2012 in “Molecular Medicine Reports” DHT affects hair follicle cells by changing microRNA levels, leading to less cell growth and more cell death.
70 citations,
January 2014 in “International review of cell and molecular biology” Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.
14 citations,
April 2016 in “Cell Transplantation” Neural stem cell extract can safely promote hair growth in mice.
2 citations,
January 2014 in “Springer eBooks” The book details skin conditions in older adults, their link to mental health, cancer treatment importance, hair loss remedies, and managing autoimmune and itchy skin.
Different types of sun exposure can damage skin cells and affect healing, with chronic exposure being more harmful, and certain immune cells help in the repair process.
14 citations,
October 2020 in “Scientific reports” Hair greying is linked to reduced ATM protein in hair cells, which protects against stress and damage.
218 citations,
January 2013 in “The Lancet Oncology” Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Aged individuals heal wounds less effectively due to specific immune cell issues.
November 2023 in “IntechOpen eBooks” Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.
112 citations,
May 2019 in “Pharmacological Research” Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.
November 2021 in “Current Otorhinolaryngology Reports” New treatments for hair loss could involve using stem cells and a process called the Wnt/beta-catenin pathway to stimulate hair growth.
488 citations,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
22 citations,
April 2017 in “Journal of Investigative Dermatology” Non-coding RNAs are crucial for skin development and health.
31 citations,
August 2021 in “Stem Cell Research & Therapy” The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.