June 2026 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This review highlights that various components of "skin boosters," such as exosomes and hyaluronic acid, may have potential applications beyond aesthetics, acting as adjunct therapies for improving skin integrity and promoting tissue regeneration, though more research is needed to support their use as primary treatments.
May 2026 in “Journal of Cosmetic Dermatology” This narrative review found that skin boosters, including hyaluronic acid and other agents, improve skin hydration, elasticity, and texture with favorable safety, though evidence is limited by study heterogeneity and lacks standardized protocols, suggesting a need for further clinical research.
April 2024 in “Biomolecules” This review summarizes recent findings on the role of mesenchymal stem cell-derived exosomal microRNAs in skin regeneration and rejuvenation, discussing their potential for treating skin damage and aging, and exploring bioengineering methods to enhance therapeutic effects.
22 citations
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July 2024 in “Archives of Plastic Surgery” This review detailed the types and mechanisms of injectable "skin boosters" and evaluated their effectiveness and safety for mitigating age-related skin changes, providing insight into their use in contemporary dermatological practice.
7 citations
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August 2018 in “Journal of Cosmetic and Laser Therapy” This study proposes an innovative treatment for stretch marks by combining skinbooster and microneedling techniques, which induce tissue remodeling and collagen synthesis, and suggests using confocal microscopy as a valuable tool for monitoring skin changes in aesthetic dermatology.
1 citations
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January 2024 in “Egyptian Dental Journal /Egyptian Dental Journal” This study observed that injecting minimally cross-linked hyaluronic acid with PDO smooth threads in female patients with dry, cracked lips led to significant improvements in lip texture, elasticity, and reduced fissure depth, effects that lasted up to nine months with additional booster injections.
1 citations
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April 2025 in “JOJ Dermatology & Cosmetics” In this study, researchers evaluated the efficacy of a collagen booster used alongside CO2 fractional laser treatment for skin aging, finding that the combination treatment affected the vascularization and healing process of the skin on a healthy adult's forearm.
June 2026 in “Drug Delivery and Translational Research” This study developed a spring-driven microneedle booster that improved early and cumulative delivery of minoxidil, accelerating hair regrowth compared to traditional roller methods in an androgenetic alopecia model.
34 citations
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October 2004 in “Plastic and Reconstructive Surgery” In this study, composite grafts were effectively used for reconstructing lower third nasal defects, providing good aesthetic outcomes with minimal complications and avoiding long scars associated with larger flaps.
2 citations
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September 2023 in “JMIR. Journal of medical internet research/Journal of medical internet research” This study reported that AutoML effectively modeled itching and pain development, as well as app use, in patients with chronic eczema or psoriasis using a smartphone monitoring app, revealing that factors like BMI, age, and disease activity significantly influenced app engagement.
11 citations
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November 2023 in “Skin Research and Technology” A 2 mm needle is effective and precise for skin injections.
August 2026 in “Journal of Cosmetic Dermatology” This animal study found that transparent porcine-derived Type I atelocollagen increases skin thickness and regenerates elastic fibers in aged mice, suggesting its potential as a skin booster for rejuvenation.
January 2024 in “International journal of advanced biochemistry research” In this study, eight dogs with severe itching and skin issues caused by Demodex canis mites showed partial improvement after one month and full recovery in two months following treatment with fluralaner, antibiotics, immune boosters, and omega supplements.
May 2020 in “International journal of current microbiology and applied sciences” This case report describes a 3-year-old pug with mixed Demodicosis and Staphylococcal infections that recovered completely after two months of combined antiparasitic, antibacterial, anti-inflammatory treatment, and supportive therapy.
December 2025 in “Clinical Case Reports” The exosome injections were from stem cells and plants, not umbilical cords.
18 citations
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September 2016 in “International Journal of Molecular Sciences” This study reports that PDRN, commonly used for wound healing, may also have anti-melanogenesis and potential skin whitening effects in both experimental models and clinical settings.
May 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Hair can regrow in adult mice's skin after injury, and this process can be boosted by increasing Wnt7a, a protein. This could potentially help treat baldness and change our understanding of hair growth.
January 2026 in “Aging and Disease” This study highlights the critical role of mitochondria in skin aging and wound repair, suggesting that targeted interventions such as antioxidants, NAD⁺ boosters, and NRF2-based therapies may enhance mitochondrial function and improve cutaneous health.
15 citations
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July 2004 in “AIDS” This case report describes a black HIV-2 patient who experienced reversible nail, hair, and skin hyperpigmentation linked to ritonavir-boosted indinavir therapy, which resolved after discontinuation.
April 2023 in “JIVA : journal of Indian Veterinary Association Kerala/JIVA :Journal of Indian Veterinary Association, Kerala” This case study reported the successful recovery of a Doberman Pinscher with skin lesions, demodicosis, pyoderma, and malasseziosis following treatment with fluralaner, enrofloxacin, shampoos, immune boosters, and fatty acids.
14 citations
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August 2020 in “Journal of cosmetic dermatology” This consensus report provides detailed recommendations for using Polynucleotides Highly Purified Technology™ in aesthetic skin rejuvenation, highlighting its potential as a biostimulatory booster for face and body revitalization.
8 citations
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November 2024 in “Journal of Cosmetic Dermatology” This article reviews the latest data on non-invasive body rejuvenation techniques, discussing advancements in filler technology and offering insights into their effectiveness and safety for both practitioners and patients interested in non-surgical procedures.
January 2024 in “International journal of advanced biochemistry research” This study observed eight dogs with severe itching, hair loss, and skin lesions that had not responded to previous treatments. After treating the dogs with fluralaner, antibiotics, immune boosters, and omega supplements, partial recovery was seen in one month, with full recovery in two months.
2 citations
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January 2017 in “Journal of Cosmetics, Dermatological Sciences and Applications” In this study, TrichotechTM, a phytocomplex derived from essential oils, enhanced fibroblast proliferation, increased FGF-7 and FGF-10 gene expression, and boosted collagen content in cultured human fibroblasts.
4 citations
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April 2018 in “Journal of Investigative Dermatology” This study suggests that hydroxypinacolone retinoate (HPR) may be an effective alternative to tretinoin for anti-aging skin treatments, offering similar collagen production benefits without increased skin irritation.
2 citations
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April 2024 in “Advanced Materials” This study tested a hydrogel microneedle patch delivering T reg attractants in mice with alopecia, finding it boosted regulatory T cell numbers at the site, leading to hair regrowth without causing peripheral immunosuppression, suggesting a potential new approach for autoimmune skin disease treatment.
1 citations
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July 2023 in “Cytotherapy” In this study, MSC-derived magnetic nanovesicles combined with a magnetic field increased skin retention and accelerated hair follicle growth in a mouse model of hair regeneration.
March 2022 in “Research Square (Research Square)” This study found that 4-aminopyridine significantly improved skin wound healing by enhancing wound closure, tissue regeneration, and cellular interactions involved in repair processes.
April 2023 in “Journal of Investigative Dermatology” This study found that mRNA booster vaccinations for SARS-CoV-2 increased protective antibodies without worsening autoimmune disease activity in patients with pemphigus and bullous pemphigoid.
November 2021 in “Research Square (Research Square)” This study found that 4-aminopyridine significantly improves skin wound healing by enhancing various cellular and molecular processes, suggesting its potential for rapid translational development in wound treatment.