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Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

Chemicals called 4-(alkylthio)- and 4-(arylthio)-benzonitrile derivatives can potentially reduce oil production on skin, which could help treat conditions like acne and hair loss.

Diphenyl ethers can potentially reduce excess oil production when applied on the skin, helping treat conditions like acne.

The document explains different hair and scalp conditions, including common hair loss after pregnancy or illness, drug-induced hair loss, hereditary excessive hair growth, patterned baldness, autoimmune hair loss, and permanent loss due to skin disease, with generally limited treatment options.

A rare skin disorder, Ichthyosis with confetti, has no cure but treatment focuses on managing symptoms with moisturizers.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Acne is strongly linked to high BMI, hair loss, menstrual issues, family history, and eating too many sweets and fatty foods, but not to excessive hair growth.

Emollients can make fabrics more flammable, so take safety precautions.

A Nigerian baby with neonatal lupus got better with treatment by 6 months.

An adult had a rare scalp infection in the forehead area, treated successfully with itraconazole.

Severe male pattern hair loss is linked to lower hair density in the back of the head.

Some skin diseases and anaemia are related, and treating the skin condition can often improve the anaemia.

People with cutaneous Lichen Planus are more likely to have Metabolic Syndrome and related conditions like high cholesterol, diabetes, and high blood pressure.

Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.

Pregnancy can cause unique skin issues, some of which may risk the mother and baby's health and need careful treatment.

A pregnant woman with Werner's syndrome died during childbirth, but her baby survived and did not have the syndrome.

Maternal aspartame consumption during pregnancy leads to skin damage and higher apoptosis in newborn rat offspring.

Skin changes can indicate starvation and nutritional deficiencies in anorexia nervosa.

Fat-related cells are important for initiating hair growth.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

BMP2 and BMP7 have opposite roles in feather formation.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

Macrophages are essential for successful skin growth in reconstructive surgery.

Changing light exposure can affect hair growth timing in goats, possibly due to a key gene, CSDC2.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

Adult skin cell-based early-stage skin substitutes improve wound healing and hair growth in mice.

Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.