research Interleukin 6 and STAT3 Regulate p63 Isoform Expression in Keratinocytes During Regeneration
The conclusion is that the IL-6/STAT3 activation affects p63 expression in healing wounds, which may help in hair follicle regeneration.
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720-750 / 1000+ results research CFTR Potentiator Ivacaftor Protects Against Noise-Induced Hair Cell Loss by Increasing Nrf2 and Reducing Oxidative Stress
Ivacaftor can protect against noise-induced hearing loss by reducing oxidative stress.
research Weekly Treatment with SAMiRNA Targeting the Androgen Receptor Ameliorates Androgenetic Alopecia
A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.
research Editorial: Synthesis, Functionalization, and Clinical Translation of Pharmaceutical Biomaterials
New pharmaceutical biomaterials, especially nanomaterials, show promise for improving cancer treatment and disease diagnosis.
research When Bugs and Drugs Conspire: Driving Acneiform Skin Toxicity
Certain cancer drugs interact with skin bacteria to cause acne-like rashes.
research The Latest Reports on Androgenetic Alopecia
New treatments for common hair loss are needed.
research HPV8 E6 Induced STAT3 Activation Leads to Hair Follicle Junctional Zone Keratinocyte Stem Cell Proliferation and Expansion in Actinic Keratoses
HPV8 causes hair follicle stem cells to grow, leading to skin lesions.
research Controlling MTORC1 Activity as a Novel Therapeutic Strategy for Managing Human Hair Growth and Pigmentation
Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.
research After Skin Wounding, Noncoding dsRNA Coordinates Prostaglandins and WNT7b to Promote Regeneration
Double stranded RNA helps skin wounds heal by coordinating specific proteins and signaling pathways.
research EZH2 Is Required for Human Hair Follicle Growth and Epidermal Differentiation
EZH2 is essential for hair growth and skin cell development.
research Is Intrafollicular Autophagy an Essential Mechanism That Permits Human Hair Follicles to Remain in Prolonged Anagen In Vivo?
Autophagy, a cell recycling process, is crucial for prolonged hair growth and could be a potential target for treating hair growth disorders.
research Transcriptomic Profiling of Frontal and Occipital Dermal Papilla Reveals Potential Role of TRPS1 in Androgenic Alopecia
TRPS1 loss in balding scalp areas contributes to hair loss in androgenic alopecia.
research Up-Regulation of Androgen Receptor by Heat Shock Protein 27 and miR-1 Induces Pathogenesis of Androgenic Alopecia
Higher levels of heat shock protein 27 and lower levels of miR-1 can increase AR levels, leading to hair loss in men.
research Cell Death by Cornification
Cornification is how skin cells die to form the protective outer layer of skin, hair, and nails.
research Fibroblast Growth Factors: Key Players in Regeneration and Tissue Repair
Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
research In Vivo Function of VDR in Gene Expression: VDR Knock-Out Mice
Vitamin D receptor is crucial for bone health and mineral metabolism.
research Dissolving Microneedles: Applications and Growing Therapeutic Potential
Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
research Frontiers in Alopecia Areata Pathobiology Research
The review suggests that other immune cells besides CD8+ T cells may contribute to alopecia areata and that targeting regulatory cell defects could improve treatment.
research Nanomaterial-Based Therapy for Wound Healing
Nanomaterials show promise in improving wound healing but require more research on their potential toxicity.
research Long And Short Non-Coding RNA And Radiation Response: A Review
Non-coding RNAs could help detect and treat radiation damage.
research Birt-Hogg-Dubé Syndrome: From Gene Discovery to Molecularly Targeted Therapies
New therapies for Birt–Hogg–Dubé syndrome are being developed based on understanding the FLCN gene's role.
research Extracellular Vesicles from Activated Dermal Fibroblasts Stimulate Hair Follicle Growth Through Dermal Papilla-Secreted Norrin
Special particles from skin cells can promote hair growth by activating a specific growth signal.
research Current Advances of Nanocarrier Technology-Based Active Cosmetic Ingredients for Beauty Applications
Nanocarrier technology in cosmetics improves ingredient delivery and effectiveness while reducing side effects.
research Effect of P144 (Anti-TGF-β) in an In Vivo Human Hypertrophic Scar Model in Nude Mice
P144® improves hypertrophic scars by reducing size and thickness and increasing elasticity.
research Androgens Induce Sebaceous Differentiation in Sebocyte Cells Expressing a Stable Functional Androgen Receptor
Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
research Overview of Urethral Reconstruction by Tissue Engineering: Current Strategies, Clinical Status, and Future Direction
The best method for urethral reconstruction is using hypoxia-preconditioned stem cells with autologous cells on a vascularized synthetic scaffold.
research Phospholipase A2 in Skin Biology: New Insights from Gene-Manipulated Mice and Lipidomics
Phospholipase A2 enzymes play key roles in skin health and disease.
research Electrospun Scaffold of Collagen and Polycaprolactone Containing ZnO Quantum Dots for Skin Wound Regeneration
The new wound dressing helps skin heal faster and fights infection.
research Activation of Androgen Receptor Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
Breast cancer treatments work better with AR activation, improving results and reducing side effects.
research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.