December 2020 in “Journal of Skin and Sexually Transmitted Diseases” This study found no significant correlation between serum testosterone or DHEAS levels and the severity of acne or FPHL in a localized female population, but noted most patients had low testosterone levels.
January 2016 in “Global dermatology” A treatment called Cellcurin, combined with microneedling, significantly increased hair density and diameter in patients with hair loss.
7 citations
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August 2003 in “Der Hautarzt” 1 citations
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January 2018 in “Journal of Cosmetics Dermatological Sciences and Applications” This study observed that a targetoid polycyclic concentric hair regrowth pattern appeared in some male patients with alopecia areata following treatment, indicating a positive sign of recovery despite unclear etiopathogenesis.
April 2025 in “Pharmaceuticals” This study found that novel thiol-reactive cross-linking agents, particularly APA, significantly improved the tensile strength and elasticity of human hair fibers by effectively regenerating disulfide bridges, with potential applications for advanced hair repair treatments in the cosmetic industry.
January 2024 in “International Journal of Trichology” In this study, researchers reviewed the evidence linking COVID-19 with dermatologic conditions like androgenetic alopecia and concluded that most proposed associations lack convincing statistical support, challenging the idea of these as independent risk factors for COVID-19 severity.
January 2020 in “Egyptian Journal of Dermatology and Venereology” This study found that increased expression of the stem cell factor receptor c-kit was associated with alopecia areata and androgenic alopecia, suggesting it may have a predictive role in progression among high-risk patients.
February 2026 in “Nature Communications” This study combined spatial and single-cell transcriptomics to identify that hypercontractility of the connective tissue sheath activates PIEZO1 in hair follicles, leading to miniaturization in male androgenetic alopecia, and found that inhibiting this contraction improves hair growth in models.
This study found that frequent consumption of sweetened tea drinks is linked to an increased risk of female androgenetic alopecia, with the risk further heightened by late bedtimes, but sleep behavior rather than sugar intake mediates the association.
In a systematic review and meta-analysis, this study reported that oral spironolactone showed a 56.60% overall improvement in female pattern hair loss, with better results in combination therapy, but emphasized the need for more research due to varied treatment responses and adverse event rates.
48 citations
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January 2017 in “International Journal of Trichology” This study found that combining microneedling with PRP and topical minoxidil (5%) significantly improved hair growth in men with androgenetic alopecia compared to using minoxidil alone.
20 citations
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October 2024 in “British Journal of Dermatology” In this updated guideline, the British Association of Dermatologists' expert group provided 49 management recommendations for alopecia areata and highlighted future research priorities, aiming to improve care for individuals affected by this condition.
17 citations
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November 2021 in “Journal of Cosmetic Dermatology” This review discusses treatment options for androgenetic alopecia, highlighting the need for personalized, evidence-based approaches but reports no new clinical results.
15 citations
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July 2022 in “Biomedicines” This study found no significant difference in the severity of alopecia areata between treatments with platelet-rich plasma and triamcinolone acetonide; further high-quality trials of PRP are needed.
12 citations
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January 2019 in “International Journal of Trichology” This study found that trichoscopy revealed significant differences in certain variables, such as the brown peripilar sign and white peripilar sign, which may aid in diagnosing early and late stages of androgenetic alopecia.
8 citations
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August 2022 in “Microorganisms” This study reports that drug repurposing for COVID-19 has had mixed results, with success for some drugs but a lack of clinical efficacy for others, highlighting the need for improved preclinical profiling and a standardized drug development platform for future antiviral treatments.
5 citations
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January 2020 in “International Journal of Trichology” This study found that both microneedling and microneedling with platelet-rich plasma improved hair thickness and density in male pattern alopecia, but no additional benefit was observed with the addition of platelet-rich plasma.
4 citations
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March 2023 in “Journal of Cosmetic Dermatology” This narrative review discusses carboxytherapy, highlighting its potential benefits in treating various dermatologic and cosmetic conditions such as skin aging, cellulite, and alopecia. Reportedly, this minimally-invasive treatment facilitates skin rejuvenation through vasodilatation and collagen reorganization.
4 citations
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January 2025 in “JAAD reviews.” This review discusses how JAK inhibitors, like tofacitinib and baricitinib, show promise in improving conditions like lichen planopilaris and frontal fibrosing alopecia by reducing severity scores and enhancing hair regrowth, though further research on safety and personalized approaches is needed.
2 citations
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April 2025 in “Biologics” This study reviewed clinical trials and reports on cytokine-targeting biologics for alopecia areata, finding Dupilumab and Ustekinumab showed strong efficacy, while other biologics had limited success or worsened the condition. Further research is needed to optimize biologic therapies for AA.
1 citations
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September 2021 in “Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria” This study found that the prevalence of androgenetic alopecia among adults in Ogbomoso, Nigeria, was 29.95%, with a higher incidence in men and mixed type baldness as the most common phenotype.
1 citations
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January 2020 in “Egyptian Journal of Dermatology and Venereology” This study found that men with androgenetic alopecia had higher serum levels of testosterone and DHT compared to controls, suggesting a significant role of serum androgens in AGA development and progression.
April 2026 in “Cosmetics” In this randomized, double-blind, placebo-controlled trial, researchers found that a multi-targeted cosmetic formulation containing TrinogeniX™ significantly increased hair density and thickness in individuals with androgenetic alopecia without adverse effects, suggesting it as a potential safe and effective treatment option.
This study found that a combination of topical and oral treatment led to greater improvements in hair density, thickness, and anagen/telogen ratio in patients with androgenetic alopecia compared to topical treatment alone, with significant benefits observed over a 3-month period.
July 2025 in “The Journal of Dermatology” This study reported that 5% topical minoxidil lotion may be beneficial for enhancing hair regrowth in patients with telogen effluvium, although its effectiveness is limited by the self-healing nature of the condition and the small sample size.
October 2024 in “Frontiers in Nutrition” This study found that patients with alopecia, particularly alopecia areata and female pattern hair loss, often have vitamin D deficiency, suggesting that screening for vitamin D could benefit these patients.
April 2024 in “Nigerian Postgraduate Medical Journal” This review summarizes existing knowledge on androgenetic alopecia, including its epidemiology, pathophysiology, and management, but presents no new research findings.
May 2023 in “Journal of Clinical Medicine” This review article reports recent advancements in understanding, diagnosing, and treating various hair loss conditions, like androgenetic alopecia and alopecia areata, including their genetic factors and new therapeutic options, while also examining the impact of COVID-19 on hair loss.
December 2025 in “Phytomedicine Plus” This review summarizes recent advances in alopecia management, focusing on combining synthetic and herbal therapies with innovative drug delivery systems like nanocarriers to enhance effectiveness and reduce side effects, while noting challenges with skin penetration and bioavailability.
November 2025 in “British Journal of Dermatology” This guideline by the British Association of Dermatologists reviews managing alopecia areata and provides 56 recommendations but reports no new clinical results.