Targetoid Polycyclic Concentric Hair Regrowth Pattern Is a Sign of Immunological Recovery in Alopecia Areata

January 2018 in “ Journal of Cosmetics Dermatological Sciences and Applications ”

Khalifa E. Sharquie, Raheeq K. Ahmed, Inas K. Sharquie

alopecia areata targetoid polycyclic concentric hair regrowth immunological recovery triamcinolone clobetasone zinc sulfate steroid injection topical steroid zinc supplement

TLDR A targetoid hair regrowth pattern indicates recovery in alopecia areata.

The study observed a targetoid polycyclic concentric hair regrowth pattern in 7 male patients with alopecia areata, aged 4 to 25 years, as a sign of immunological recovery following treatment. This pattern, characterized by alternating circles of complete and incomplete hair regrowth, was considered rare and indicative of recovery. The study suggested that this phenomenon might be due to regional variations in immune response, where areas with a stronger immune reaction show less hair regrowth, while areas with a normal response show more complete regrowth. The findings supported the hypothesis that this pattern is a result of alternating immunological reactions in alopecia areata patches.

View this study on scirp.org →

Discuss this study in the Community →

Research cited in this study

6 / 6 results

research Clinical Observations in Alopecia Areata: Implications and Hypotheses

10 citations , September 2014 in “Australasian Journal of Dermatology”

Understanding alopecia areata's patterns can improve future research and treatments.

research Overview of Alopecia Areata

110 citations , December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.

research Unusual Forms of Alopecia Areata in a Trichology Unit

7 citations , August 2013 in “Journal of the European Academy of Dermatology and Venereology”

Less than a quarter of alopecia areata cases were unusual forms or had paradoxical regrowth.

research Annular Alopecia Areata: Report of Two Cases

8 citations , January 2013 in “International journal of trichology”

Two people had unusual ring-shaped hair loss due to an autoimmune disorder.

research Regrowth of Black Hair in Two Red-Haired Alopecia Areata Patients

5 citations , February 2012 in “Australasian Journal of Dermatology”

Two red-haired men with alopecia areata regrew black hair instead of red.

research Two Cases of Linear Alopecia on the Occipital Scalp

26 citations , January 2009 in “Annals of Dermatology”

Two rare bald spots on the back of the scalp were found to be lupus, not alopecia areata.

Related Community Posts Join

6 / 1000+ results

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

nkrata in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community To anyone that is still not seeing results on the big 3…

in Treatment 109 upvotes 3 years ago

User redh0t12 suggests using a derma pen for hair regrowth, as it helped them after using finasteride and minoxidil. Others discuss their experiences with various treatments, including derma rolling, oral and topical minoxidil, and finasteride, with mixed results.

community Can I punch someone if they make fun of my hair loss, just like Will Smith did?

in Chat 448 upvotes 3 years ago

Hair loss's social impact, focusing on Will Smith defending Jada Pinkett Smith's alopecia. The conversation highlights double standards between men and women experiencing hair loss and emphasizes empathy.

community Survived First Monte. Shedding is real

in Progress Pictures 370 upvotes 1 year ago

The user is treating hair loss with 1mg finasteride every other day, daily topical minoxidil, and weekly derma rolling, and is considering using hair fibers for special occasions. There is a discussion about the initial shedding phase of minoxidil treatment and the importance of consistent photo conditions to track progress.

community DUPA/Retrograde might not be DHT based...GET A BIOPSY QUICK or permanent Hair Loss!

in Research/Science 39 upvotes 1 year ago

DUPA and retrograde alopecia may not be solely DHT-based, and a biopsy is crucial for accurate diagnosis and treatment. Treatments mentioned include dutasteride, oral minoxidil, pioglitazone, clobetasol, calcipotriol, ketoconazole, and doxycycline, depending on the specific condition.

community People need to start accepting that only medical therapy (Fin/Dut) can save your hair in the long run.

in Treatment 112 upvotes 2 years ago

Minoxidil can regrow hair but doesn't address the underlying issue of DHT, leading to continued hair loss. Users discuss their experiences with finasteride and dutasteride, mentioning side effects, personal outcomes, and alternatives like microdosing topical finasteride.

Related Research

3 / 3 results

research Alopecia Areata: A Multifactorial Autoimmune Condition

148 citations , December 2018 in “Journal of autoimmunity”

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

research Linear Alopecia Areata

4 citations , November 2018 in “JAAD case reports”

Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.

research Treating Resistant Cases of Alopecia Universalis

May 2018 in “Journal of cosmetology & trichology”

Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.