TLDR A targetoid hair regrowth pattern indicates recovery in alopecia areata.
The study observed a targetoid polycyclic concentric hair regrowth pattern in 7 male patients with alopecia areata, aged 4 to 25 years, as a sign of immunological recovery following treatment. This pattern, characterized by alternating circles of complete and incomplete hair regrowth, was considered rare and indicative of recovery. The study suggested that this phenomenon might be due to regional variations in immune response, where areas with a stronger immune reaction show less hair regrowth, while areas with a normal response show more complete regrowth. The findings supported the hypothesis that this pattern is a result of alternating immunological reactions in alopecia areata patches.
10 citations
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September 2014 in “Australasian Journal of Dermatology” Understanding alopecia areata's patterns can improve future research and treatments.
110 citations
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December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.
7 citations
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August 2013 in “Journal of the European Academy of Dermatology and Venereology” Less than a quarter of alopecia areata cases were unusual forms or had paradoxical regrowth.
8 citations
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January 2013 in “International journal of trichology” Two people had unusual ring-shaped hair loss due to an autoimmune disorder.
5 citations
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February 2012 in “Australasian Journal of Dermatology” Two red-haired men with alopecia areata regrew black hair instead of red.
26 citations
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January 2009 in “Annals of Dermatology” Two rare bald spots on the back of the scalp were found to be lupus, not alopecia areata.
148 citations
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December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
4 citations
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November 2018 in “JAAD case reports” Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.
May 2018 in “Journal of cosmetology & trichology” Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.