Use of 5% Topical Minoxidil Application for Telogen Effluvium: An Open-Label Single-Arm Clinical Trial

    July 2025 in “ The Journal of Dermatology ”
    Manabu Ohyama, Ryokichi Irisawa, M Uchiyama … Toru Fujita
    Studysummary This study reported that 5% topical minoxidil lotion may be beneficial for enhancing hair regrowth in patients with telogen effluvium, although its effectiveness is limited by the self-healing nature of the condition and the small sample size.
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    Research cited in this study 16

    1. Low-Dose Oral Minoxidil and Associated Adverse Events: Analyses of the FDA Adverse Event Reporting System With a Focus on Pericardial Effusions Journal of Cosmetic Dermatology · 2024
    2. Recent Advances in Understanding of the Etiopathogenesis, Diagnosis, and Management of Hair Loss Diseases Journal of Clinical Medicine · 2023
    3. Management of Hair Loss After Severe Acute Respiratory Syndrome Coronavirus 2 Infection: Insight Into the Pathophysiology With Implication for Better Management The Journal of Dermatology · 2022
    4. Oral Minoxidil Use in Androgenetic Alopecia and Telogen Effluvium Archives of Dermatological Research · 2022
    5. Telogen Effluvium: A Review of the Science and Current Obstacles Journal of Dermatological Science · 2021
    6. Telogen Effluvium: A Review of the Literature Cureus · 2020
    7. Guidelines for the Diagnosis and Treatment of Male-Pattern and Female-Pattern Hair Loss, 2017 Version Journal of Dermatology · 2018
    8. Treatment of Chronic Telogen Effluvium with Oral Minoxidil: A Retrospective Study F1000Research · 2017
    9. Hair Shedding in Women: How Much Is Too Much? British Journal of Dermatology · 2015
    10. Telogen Effluvium: A Review Journal of Clinical and Diagnostic Research · 2015
    11. Telogen Effluvium: A Review of Acute and Chronic Forms Indian Journal of Dermatology, Venereology and Leprology · 2013
    12. Hair Evaluation Methods: Merits and Demerits International Journal of Trichology · 2009
    13. Burden of Hair Loss: Stress and the Underestimated Psychosocial Impact of Telogen Effluvium and Androgenetic Alopecia Journal of Investigative Dermatology · 2004
    14. Effect of Minoxidil on Proliferation and Apoptosis in Dermal Papilla Cells of Human Hair Follicle Journal of Dermatological Science · 2004
    15. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    16. Telogen Effluvium: A Comprehensive Review Archives of Dermatology · 1993

    Related research 8

    1. Continued Year-On-Year Improvement in Hair Density With Systemic Minoxidil in Women With Female Pattern Hair Loss: A Case Series Journal of the American Academy of Dermatology · 2025
    2. Role Of Oral Minoxidil In The Treatment Of Androgenetic Alopecia Cosmoderma · 2024
    3. A Pilot Split-Scalp Study of Combined Fractional Radiofrequency Microneedling and 5% Topical Minoxidil in Treating Male Pattern Hair Loss Clinical and Experimental Dermatology · 2018
    4. 5% Minoxidil: Treatment for Female Pattern Hair Loss PubMed · 2015
    5. Androgenetic Alopecia in Adolescents PubMed · 2003
    6. Effect of Minoxidil on Hair Growth in Androgenic Alopecia in Women PubMed · 2002
    7. A Randomized Trial of Minoxidil in Chemotherapy-Induced Alopecia Journal of The American Academy of Dermatology · 1996
    8. The Use of Minoxidil to Prevent Alopecia During Chemotherapy for Gynecologic Malignancies PubMed · 1991