Serum Levels of Testosterone and Dehydroepiandrosterone Sulfate in Females with Acne and/or Female Pattern Hair Loss

December 2020 in “ Journal of Skin and Sexually Transmitted Diseases ”

Raman Balakrishna Venkatta, Sheena Ann Simon, K. Abdul Samad, Anuja Elizabeth George

testosterone dehydroepiandrosterone sulfate DHEAS female pattern hair loss FPHL acne DHEA female hair loss

TLDR No strong link between testosterone or DHEAS levels and acne or hair loss in females.

This study involving 84 females found no significant correlation between serum levels of testosterone and dehydroepiandrosterone sulfate (DHEAS) with the severity of acne or female pattern hair loss (FPHL). Most patients had low levels of total testosterone, contradicting previous studies. However, 50% of patients with both conditions had high DHEAS levels, indicating a potential role for DHEAS. The study's limitation was its setting in a tertiary referral center, which may not represent the general population.

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