Role of Serum Androgens and Prostate-Specific Antigen Levels in Men with Androgenetic Alopecia

    January 2020 in “ Egyptian Journal of Dermatology and Venereology ”
    Hesham N Khaled, Azza M Abdu Allah, Ahmad A Abdelhameed, Wafaa Ahmed Shehata
    Studysummary This study found that men with androgenetic alopecia had higher serum levels of testosterone and DHT compared to controls, suggesting a significant role of serum androgens in AGA development and progression. Our plain-language summary of this paper — not a Tressless recommendation.
    The study compared 40 men with androgenetic alopecia (AGA) to 40 healthy controls and found that serum levels of testosterone and dihydrotestosterone (DHT) were higher in AGA patients, suggesting that androgens played a significant role in AGA development. There was no significant difference in prostate-specific antigen (PSA) levels between the groups, indicating no association between AGA and prostate cancer risk. The study also noted differences in androgen levels between frontal and vertical AGA, emphasizing the need for further research to explore these relationships and develop targeted treatments.
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