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    Glossary Signal Transduction Inhibitor

    blocks cell communication pathways to prevent abnormal growth

    A Signal Transduction Inhibitor (STI) is a type of drug that blocks the communication pathways within cells, which are responsible for transmitting signals from the cell surface to the interior. These inhibitors can interfere with the processes that lead to cell growth, division, and survival, making them useful in treating conditions like cancer, where cell signaling pathways are often overactive.

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    1. Nitric Oxide Signal Transduction and Its Role in Skin Sensitization Biomolecules & therapeutics · 2023 · 1 citations
    2. Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne 2009 · 65 citations
    3. Myricetin: A Significant Emphasis on Its Anticancer Potential via the Modulation of Inflammation and Signal Transduction Pathways International Journal of Molecular Sciences · 2023 · 54 citations
    4. Unique Circulating MicroRNA Signatures Distinguish Severe Alopecia Areata from Other Inflammatory Skin Diseases Preprints.org · 2025
    5. MicroRNA control of signal transduction Nature Reviews Molecular Cell Biology · 2010 · 1066 citations
    6. A Murine Model for Inducing and Manipulating Hair Follicle Regression (Catagen): Effects of Dexamethasone and Cyclosporin A Journal of Investigative Dermatology · 1994 · 124 citations
    7. Janus Kinase Inhibitors in Dermatology: Part 1 — General Considerations and Applications in Vitiligo and Alopecia Areata Actas Dermo-Sifiliográficas · 2021 · 14 citations
    8. Flavonoids in safflower extract reduce cisplatin-induced damage to human follicle dermal papilla cells by inhibiting DNA damage and Rad17/Chk1/Cdc25C signaling Biocell · 2023
    9. A Putative Role for Fusaric Acid in Biocontrol of the Parasitic Angiosperm <i>Orobanche ramosa</i> Molecular Plant-Microbe Interactions · 2006 · 39 citations
    10. Physiological and transcriptomic analyses of brassinosteroid function in kiwifruit root Environmental and Experimental Botany · 2021 · 8 citations
    11. A Neutralizing Prolactin Receptor Antibody Whose In Vivo Application Mimics the Phenotype of Female Prolactin Receptor-Deficient Mice Endocrinology · 2015 · 14 citations
    12. 1408 INDUCTION OF SECRETED WNT FACTOR WISP1/CCN4 BY HUMAN PROSTATE STROMAL CELLS BY MICROENVIORNMENTAL HYPOXIA The Journal of Urology · 2010
    13. Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine International Journal of Molecular Sciences · 2015 · 23 citations
    14. Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues The EMBO Journal · 2002 · 111 citations
    15. The TIP GROWTH DEFECTIVE1  <i>S</i>-Acyl Transferase Regulates Plant Cell Growth in <i>Arabidopsis</i>  The Plant Cell · 2005 · 147 citations
    16. The JAK/STAT signaling pathway: from bench to clinic Signal Transduction and Targeted Therapy · 2021 · 489 citations
    17. Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways InTech eBooks · 2017 · 1 citations
    18. Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles Journal of The American Academy of Dermatology · 2008 · 18 citations
    19. LncRNA PlncRNA‑1 regulates proliferation and differentiation of hair follicle stem cells through TGF‑β1‑mediated Wnt/β‑catenin signal pathway Molecular Medicine Reports · 2017 · 25 citations
    20. Unravelling the molecular basis for symbiotic signal transduction in legumes Molecular Plant Pathology · 2006 · 27 citations
    21. Hair Growth Promoting Effects of Limosilactobacillus reuteri Isolated from Honeybee through Wnt/β-catenin Signal Transduction Journal of the Korean Society of Cosmetology · 2026
    22. Molecular basis of hypohidrotic ectodermal dysplasia: an update Journal of Applied Genetics · 2015 · 85 citations
    23. Chrousos syndrome: from molecular pathogenesis to therapeutic management European Journal of Clinical Investigation · 2015 · 47 citations
    24. IMPACT OF MERCURY ON SEX HORMONES (LITERATURE REVIEW) Bulletin of Osh State University · 2024 · 1 citations
    25. Linking diet to acne metabolomics, inflammation, and comedogenesis: an update Clinical, Cosmetic and Investigational Dermatology · 2015 · 138 citations
    26. Exercise activates the PI3K-AKT signal pathway by decreasing the expression of 5α-reductase type 1 in PCOS rats Scientific reports · 2018 · 28 citations
    27. 1407 ANDROGENETIC ALOPECIA, PROSTATE VOLUME AND URINARY SYMPTOMS. IS THERE A RELATIONSHIP? A CASE-CONTROL STUDY The Journal of Urology · 2010
    28. Mesenchymal–epithelial interactions during hair follicle morphogenesis and cycling Seminars in Cell & Developmental Biology · 2012 · 300 citations
    29. Peripheral blood gene expression in alopecia areata reveals molecular pathways distinguishing heritability, disease and severity Genes and Immunity · 2010 · 20 citations
    30. Hair Follicle Pigmentation 2005 · 450 citations