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Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.

Menopause worsens skin, hair, and nails, affecting self-esteem and quality of life.

Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.

PCOS causes infertility mainly due to hormonal imbalances, insulin resistance, and chronic inflammation.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

New treatments for male hypogonadism are effective and should be personalized.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

AGA treatments like minoxidil and LLLLT are safe and effective for gender minority patients.

Finasteride blocks deoxycorticosterone's anticonvulsant effects in infant rats, but indomethacin doesn't.

Estrogen therapy can reduce skin aging but has cancer risks.

Lowering testosterone speeds up wound healing in male mice.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Long-term finasteride use doesn't change bone density or metabolism.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Intermittent low-dose finasteride works as well as daily use for treating excessive hair growth in women.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.

Changing allopregnanolone levels in baby rats affects their adult behavior and alcohol use.

Estrogens and progesterone are key in regulating melasma pigmentation.

Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.

Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Human hair follicles can make and process prostaglandins, which may affect hair growth.