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Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Hormone therapy increases the risk of heart-related issues in transgender women and may affect heart health in transgender men.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Female pattern hair loss is caused by multiple factors and while treatments like topical minoxidil, hormone therapy, and low-level light therapy can help, none can fully cure it.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

Menopause worsens skin, hair, and nails, affecting self-esteem and quality of life.

Cancer rates are increasing in developed countries, with estrogen, aging, low vitamin D3, and HPV infection as common causes.

Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.

A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

Substances from fat-derived stem cells can promote hair growth and counteract hormone-related hair loss by activating a key hair growth pathway.

Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Oestrogens are key for bone growth during puberty in both boys and girls.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

Certain drugs change freshwater snail shells to a "banana" shape.

Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.

Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.

Exposure to plastics may increase the risk of irregular menstrual cycles and symptoms of hormone imbalance in teenage girls.

The skin produces and processes hormones, affecting both local and overall body functions.

The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.