38 citations
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January 2011 in “Endocrine Journal” This study found that serum vaspin levels were elevated in women with polycystic ovary syndrome compared to controls, but treatment with metformin or weight loss did not significantly change these levels.
11 citations
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January 2014 in “Egyptian Journal of Dermatology and Venereology” This study found that women with female-pattern hair loss had significantly lower serum levels of 25-hydroxyvitamin D compared to healthy controls, but it does not establish causation.
2 citations
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May 2022 in “Diagnostics” This study confirmed that 25(OH)D3 can be detected in hair samples from healthy young adults, but no correlation was found between hair and serum 25(OH)D3 concentrations, indicating limited potential as a standalone biomarker.
1 citations
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October 2024 in “FARMACIA” This study found that patients with age-related cataracts had significantly lower levels of manganese, selenium, vanadium, and zinc in their serum compared to healthy controls, with low serum selenium and zinc levels showing an independent association with an increased risk of cataracts.
1 citations
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June 2022 in “International Journal of Health Sciences” This study found that lower serum BDNF levels were associated with higher depression severity and more severe alopecia areata in patients.
1 citations
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January 2020 in “Egyptian Journal of Dermatology and Venereology” This study found that men with androgenetic alopecia had higher serum levels of testosterone and DHT compared to controls, suggesting a significant role of serum androgens in AGA development and progression.
1 citations
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January 2025 in “Archives of Dermatological Research” This study found that patients with alopecia areata had significantly higher serum IL-1R1 levels, IL-1R1 gene expression, and hsa-miR-19b-3p levels compared to healthy controls, suggesting these could serve as diagnostic and prognostic markers for the disease's severity.
July 2025 in “The Egyptian Journal of Hospital Medicine” This study found that serum GPER-1 levels may serve as a biomarker for differentiating androgenetic alopecia from telogen effluvium and healthy controls, although its ability to distinguish between AGA and TE is limited.
December 2025 in “AL-QADISIYAH MEDICAL JOURNAL” This study found that patients with alopecia areata had higher serum levels of interleukin-17 and interleukin-23 compared to healthy controls, suggesting these cytokines may play a role in the disease's pathophysiology.
December 2025 in “AL-QADISIYAH MEDICAL JOURNAL” The study conducted at Al-Diwaniya Teaching Hospital found that patients with alopecia areata exhibited significantly higher serum levels of interleukin-17 and interleukin-23 compared to healthy controls, suggesting these cytokines might play a role in the disease's pathophysiology.
August 2022 in “Clinical and Experimental Dermatology” This study found that serum cysteine levels were not lower in patients with chronic telogen effluvium and did not correlate with hair loss severity.
July 2021 in “Archives of Dermatological Research” This study found that serum GPER-1 levels were significantly higher in patients with androgenetic alopecia compared to healthy controls, suggesting a potential role in the condition's pathogenesis, independent of gender.
December 2024 in “Asian Journal of Medical Sciences” This study observed that a majority of female patients with chronic telogen effluvium had low serum ferritin levels without signs of clinical anemia, suggesting a possible link between low iron stores and hair loss.
October 2021 in “International Journal of Research in Dermatology” This study found that individuals with alopecia areata had significantly lower vitamin D levels compared to healthy controls, and lower vitamin D levels were associated with more severe hair loss.
2 citations
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March 2018 in “Clinical Nutrition ESPEN” This study among ethnic Saudi Arabian women concluded that symptoms like muscle cramps, fatigue, mood swings, hair loss, back pain, and weight gain were more common in those with lower vitamin D levels.
1 citations
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January 1985 in “IRIS UNIMORE (University of Modena and Reggio Emilia)” January 2017 in “International Journal of Trichology” This study observed that serum Vitamin D3 levels were low among South Indian students with diffuse hair fall, highlighting global hypovitaminosis D as a concern and suggesting possible dietary or sunlight exposure influences.
March 2023 in “Pakistan Journal of Medical and Health Sciences” This study found that premenopausal women with female-pattern hair loss had significantly lower serum vitamin D levels compared to healthy controls, suggesting a potential role of vitamin D deficiency in this condition.
10 citations
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September 2022 in “Indian Journal of Clinical Biochemistry” 3 citations
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January 2015 in “Journal of the Egyptian Womenʼs Dermatologic Society” July 2026 in “Journal of Investigative Dermatology”
78 citations
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August 2012 in “Human molecular genetics online/Human molecular genetics” This study found that three genetic loci, including the newly identified JMJD1C, are associated with circulating testosterone and dihydrotestosterone levels, explaining a small portion of their variance in European men.
21 citations
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June 2011 in “Journal of child neurology” This study found that while serum zinc levels were lower in children treated with valproic acid or carbamazepine than in healthy controls, zinc, biotin, and biotinidase enzyme activity remained within normal ranges and unaffected by these treatments.
9 citations
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February 2020 in “International Journal of Endocrinology” This study found that men with early-onset androgenetic alopecia and certain risk factors may have worse gonadal steroidogenesis and an increased likelihood of developing gonadal dysfunction, suggesting a male equivalent of polycystic ovarian syndrome.
7 citations
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August 2021 in “Open Access Macedonian Journal of Medical Sciences” In this case–control study, the researchers in Ukraine found no significant link between VDR rs2228570 polymorphism and decreased serum BDNF levels, though they observed a moderate correlation between serum BDNF and 25-OH Vitamin D levels in patients with thyroid disorders.
1 citations
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July 2022 in “Clinical and Experimental Dermatology” This study suggests that arginine and cysteine deficiency is not present in women with chronic telogen effluvium, indicating that amino acid supplementation may be unnecessary in nutrient-replete populations.
July 2022 in “Research Square (Research Square)” This study found that Egyptian women with frontal fibrosing alopecia had lower serum PPARγ levels and a higher occurrence of PPARG gene polymorphism compared to healthy controls, suggesting a potential role for PPARγ in the condition's development.
March 2022 in “IP Indian journal of clinical and experimental dermatology” This study found that ferritin and cobalamin levels were better indicators than hemoglobin in assessing chronic nonscarring hair loss in females of reproductive age.
13 citations
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September 2009 in “Heart & Lung” This case study reports the first known instance of adult Kawasaki's disease presenting with highly elevated serum ferritin levels and splenomegaly, emphasizing its consideration in differential diagnoses for adults with persistent rash, fever, and specific clinical features.
4 citations
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March 2018 in “PloS one” This study found that among men over 70, certain genetic variants associated with skin pigmentation affect serum PSA levels, with implications for how sun sensitivity and exposure may influence prostate cancer risk.