The Influence of Valproic Acid and Carbamazepine Treatment on Serum Biotin and Zinc Levels and on Biotinidase Activity

    June 2011 in “ Journal of child neurology ”
    Manuel Castro‐Gago, Laura Pérez-Gay, Carmen Gómez-Lado … Santiago Rodrı́guez-Segade
    Studysummary This study found that while serum zinc levels were lower in children treated with valproic acid or carbamazepine than in healthy controls, zinc, biotin, and biotinidase enzyme activity remained within normal ranges and unaffected by these treatments.
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    Research cited in this study 6

    1. Serum Biotinidase Activity in Children Treated With Valproic Acid and Carbamazepine Journal of child neurology · 2009
    2. The Influence of Valproic Acid Treatment on Hair and Serum Zinc Levels and Serum Biotinidase Activity European journal of paediatric neurology · 2008
    3. The Effects of Biotin Supplementation on Serum and Liver Tissue Biotinidase Enzyme Activity and Alopecia in Rats Treated with Valproic Acid Brain & development · 2008
    4. Serum and Liver Tissue Biotinidase Enzyme Activity in Rats Administered Valproic Acid Brain & development · 2006
    5. Low Serum Biotinidase Activity in Children with Valproic Acid Monotherapy Epilepsia · 2001
    6. Alopecia and Mood Stabilizer Therapy Annals of Clinical Psychiatry · 1996

    Related research 1

    1. The Influence of Valproic Acid and Carbamazepine Treatment on Serum Biotin and Zinc Levels and on Biotinidase Activity Journal of child neurology · 2011