Serum and Liver Tissue Biotinidase Enzyme Activity in Rats Administered Valproic Acid

    May 2006 in “ Brain & development
    Nadir Korkmazer, Sebahattin Vurucu, Erkan Demirkaya … Erdal Gökçay
    Studysummary The authors concluded that administering biotin may help prevent alopecia caused by reduced biotinidase activity during valproic acid therapy in rats.
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    Research cited in this study 2

    1. Low Serum Biotinidase Activity in Children with Valproic Acid Monotherapy Epilepsia · 2001
    2. Alopecia and Mood Stabilizer Therapy Annals of Clinical Psychiatry · 1996