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GlossaryValproic Acid (Depakote)

medication used to treat epilepsy and bipolar disorder

Valproic Acid, also known as VPA or by brand names like Depakote, is a medication primarily used to treat epilepsy, bipolar disorder, and to prevent migraine headaches. It works by increasing the levels of certain neurotransmitters in the brain, which helps stabilize electrical activity and mood. Additionally, Valproic Acid has been studied for its potential effects on hair growth, as it may influence pathways involved in hair follicle cycling.

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research Cosmetic Effects of Anti-Epileptic Drugs Among Adult Sudanese Epileptic Patients

June 2021 in “Research Square (Research Square)”

Sudanese epilepsy patients often experience hair loss from anti-epileptic drugs but continue their medication regardless of cosmetic side effects.

Changes in Growth and Distribution of Hair Associated with Psychotropic Drug Use

research Changes in Growth and Distribution of Hair Associated with Psychotropic Drug Use

6 citations, October 1997 in “CNS Drugs”

Psychotropic drugs can cause hair loss or excessive hair growth.

research Cosmetic Side Effects of Antiepileptic Drugs in Adults With Epilepsy

46 citations, December 2014 in “Epilepsy & behavior”

Some antiepileptic drugs can cause weight gain and hair loss, especially in women.

research Frequency of Sodium Valproate-Induced Hair Loss and Curly Hair

6 citations, June 2005

Sodium valproate caused hair loss and curly hair in 3.5% of patients.

research Perampanel-Induced Hair Curling in a Patient with Epilepsy Associated with Pitt Hopkins Syndrome

1 citations, October 2019 in “Epileptic disorders”

A girl with Pitt-Hopkins syndrome developed curly hair as a rare side effect from the epilepsy drug perampanel.

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