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    Glossary Biotinidase

    enzyme recycling biotin, crucial for metabolism and hair health

    Biotinidase is an enzyme that plays a crucial role in recycling biotin, a B-vitamin essential for the body's metabolism of fats, carbohydrates, and proteins. Deficiency in biotinidase can lead to biotin deficiency, which may cause symptoms like hair loss, skin rashes, and neurological issues. This enzyme's activity is vital for maintaining adequate biotin levels and overall metabolic health.

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    1. Phenotypic variation in biotinidase deficiency 1983 · 184 citations
    2. Biotin and biotinidase deficiency Expert Review of Endocrinology & Metabolism · 2008 · 166 citations
    3. Biotinidase Deficiency: Prevalence, Impact And Management Strategies. PubMed · 2020 · 89 citations
    4. Partial biotinidase deficiency: Clinical and biochemical features The Journal of Pediatrics · 1990 · 86 citations
    5. Low Serum Biotinidase Activity in Children with Valproic Acid Monotherapy Epilepsia · 2001 · 73 citations
    6. Biotinidase deficiency: a survey of 10 cases. Archives of Disease in Childhood · 1988 · 72 citations
    7. The influence of valproic acid treatment on hair and serum zinc levels and serum biotinidase activity European journal of paediatric neurology · 2008 · 36 citations
    8. Late presentation of biotinidase deficiency with acute visual loss and gait disturbance Developmental Medicine & Child Neurology · 1997 · 31 citations
    9. The effects of biotin supplementation on serum and liver tissue biotinidase enzyme activity and alopecia in rats which were administrated to valproic acid Brain & development · 2008 · 22 citations
    10. The Influence of Valproic Acid and Carbamazepine Treatment on Serum Biotin and Zinc Levels and on Biotinidase Activity Journal of child neurology · 2011 · 21 citations
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