September 2025 in “Journal of Clinical Medicine” This study found that patients with vitiligo and alopecia areata had significantly higher serum granulysin levels compared to healthy controls, indicating a potential pathogenic role and suggesting that elevated levels may serve as a biomarker for monitoring disease activity, particularly in active vitiligo cases.
May 2024 in “International journal of research in dermatology” This study found that vitamin D deficiency was significantly more prevalent among men with androgenetic alopecia in eastern Uttar Pradesh, India, than in age-matched controls, suggesting a potential link between vitamin D levels and the condition's pathogenesis.
February 2023 in “El-Minia Medical Bulletin” This study found that female patients with androgenetic alopecia had significantly lower serum zinc and iron levels compared to healthy controls, suggesting supplementation may be beneficial.
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July 2015 in “International Journal of Dermatology” This study found that patients with alopecia areata had significantly lower serum zinc levels, which correlated inversely with disease severity, duration, and resistance to therapies, suggesting zinc assessment as a marker of disease status.
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June 2019 in “Journal of Cosmetic Dermatology” In this study, serum omentin-1 levels were significantly higher in females with idiopathic hirsutism compared to those with PCOS and healthy controls.
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September 2017 in “Galen medical journal” This study observed elevated serum homocysteine levels in patients with psoriasis and cutaneous-oral lichen planus compared to healthy controls, but found no significant difference between the two patient groups.
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September 2015 in “Journal of the Egyptian Women's Dermatologic Society (Print)” People with psoriasis and depression have lower BDNF levels, which could help measure depression in those with psoriasis.
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April 2021 in “International Journal of Research in Dermatology” This study found low serum ferritin and vitamin B12 levels in a significant portion of women with chronic telogen effluvium, while vitamin D deficiency was less common.
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February 2021 in “Benha Journal of Applied Sciences” This study found that ischemia-modified albumin (IMA) levels were significantly higher in patients with male pattern androgenetic alopecia compared to healthy controls, and these levels correlated with AGA duration and severity.
November 2025 in “Fayoum University Medical Journal/Fayoum University Medical Journal ” This study found that intralesional vitamin D3 injections significantly increased serum vitamin D3 levels in patients with localized alopecia areata, although baseline vitamin D3 levels did not predict disease severity or treatment response.
This study found that serum irisin levels were significantly lower in patients with androgenetic alopecia compared to healthy controls, but no significant relationship was detected between serum irisin levels and insulin resistance markers like BMI, fasting insulin, or HOMA-IR.
May 2025 in “AlQalam Journal of Medical and Applied Sciences” In this study, researchers found that while low serum ferritin levels are common among women, there was no clear association between those low levels and diffuse hair loss in patients with female pattern hair loss and chronic telogen effluvium.
May 2025 in “Health Science Reports” This study reported that applying Serum WS Biotin, a water-soluble form of D-Biotin, daily for 3 months significantly reduced hair shedding and increased hair strength in volunteers with moderate to excessive hair shedding, while showing good skin compatibility.
January 2025 in “Mansoura Medical Journal” This study examined serum ischemia-modified albumin levels in men with androgenic alopecia compared to healthy controls and found no diagnostic value, though higher levels were associated with more severe alopecia, indicating potential involvement in disease progression.
October 2024 in “Archives of Dermatological Research” The study found that patients with androgenetic alopecia had higher serum GPER-1 levels, which were associated with disease severity and duration, indicating a potential estrogen-independent role of GPER-1 in the condition's pathogenesis.
July 2024 in “The Egyptian Journal of Hospital Medicine” In this study, researchers observed that serum calprotectin levels were higher in alopecia areata patients compared to controls, yet this difference was not statistically significant, and calprotectin was not a reliable predictor of disease activity in alopecia areata patients.
January 2024 in “The Egyptian Journal of Hospital Medicine (Print)” This study found that there was no statistically significant difference in serum zinc levels between patients with pattern hair loss and healthy controls, and concluded that zinc deficiency is unlikely to be a direct cause of androgenetic alopecia.
August 2023 in “International journal of basic and clinical pharmacology” This review article describes the ingredients and evaluation tests for formulating a hair serum aimed at improving hair growth and preventing hair loss, highlighting the roles of Citrus sinensis, Nigella sativa, flax seed, and coconut oil in addressing hair and scalp health.
April 2023 in “Tikrit Journal of Pharmaceutical Sciences” In this study, researchers assessed the effects of deferasirox in 85 children with ß-thalassemia in Kirkuk and reported that while 55.3% experienced a reduction in serum ferritin, 9.4% had adverse effects, indicating that deferasirox is generally well-tolerated as an iron chelator with modifiable side effects.
July 2022 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” In this study, patients with alopecia areata were found to have significantly lower serum zinc levels compared to healthy controls, and lower zinc levels were associated with more severe disease.
July 2022 in “Al-Mağallaẗ al-ʻirāqiyyaẗ li-l-ṣaydalaẗ” In this study, patients with alopecia areata had significantly lower serum zinc levels compared to healthy controls, with an inverse relationship between zinc levels and disease severity.
March 2022 in “Benha Journal of Applied Sciences” This study suggests that the serum marker may play a role in the pathogenesis of tinea capitis and could serve as an independent risk factor for assessing vulnerability, activity, and severity of the condition.
August 2021 in “Benha Journal of Applied Sciences” This study found that biotin supplementation significantly improved hair loss in telegon effluvium patients with low serum biotin levels.
September 2020 in “Benha Journal of Applied Sciences” This study found that patients with alopecia areata had lower serum zinc and biotin levels compared to healthy controls, suggesting these deficiencies may play a role in the condition's pathogenesis.
July 2020 in “Benha Journal of Applied Sciences” This study found that patients with alopecia areata had higher serum levels of EGF compared to healthy controls, suggesting EGF's involvement in the condition's pathogenesis.
January 2019 in “Türkiye klinikleri dermatoloji dergisi” This study investigated the role of serum iron, ferritin, zinc, and folic acid levels in women with diffuse hair loss but reports no findings.
September 2018 in “International Journal of Dermatology” This study found that Iranian patients with alopecia areata had significantly lower zinc and vitamin D levels than healthy controls, indicating these nutrients' potential role in disease management.
January 2013 in “kerbala journal of pharmaceutical sciences” The researchers reported that adult menstruating females with chronic telogen effluvium had significantly lower serum zinc levels compared to healthy controls, suggesting an association between decreased zinc levels and CTE.
September 2021 in “Journal of advances in medicine and medical research” This study indicated a correlation between female pattern hair loss and decreased serum levels of Vitamin D3, suggesting that Vitamin D3 evaluation may be important in managing this condition.
July 2020 in “Benha Journal of Applied Sciences” This study found that young male patients with grade III and IV androgenetic alopecia had elevated levels of serum amyloid A3, suggesting a higher risk of developing atherosclerosis compared to those without the condition.