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Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Finasteride helps reduce lung inflammation and damage after trauma and infection.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Hesperidin protects rat testicles from finasteride damage and improves sperm health.

Oregano extract helps fix testis and sperm damage caused by finasteride.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Finasteride improves immune response and reduces organ damage after trauma hemorrhage in mice.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Antibody treatments show promise for hair loss but need more research.

The document says that early treatment of Acne Vulgaris is important to prevent scarring and that adult onset acne is common in women, often due to hormonal imbalances.

PCOS is a hormonal disorder causing infertility and menstrual problems, often linked to obesity and can lead to acne, treated with hormonal and insulin-sensitizing medications.

Researchers found new hair and nail genes, how hair reacts to UV, differences in white and pigmented hair growth, nerve changes in alopecia, treatments for baldness and alopecia, a toenail condition linked to a genetic disorder, and that nail fungus is more common in people with psoriasis.

Hair loss can indicate brain aging and potential small vessel disease, but more research is needed to understand the clinical impact.

Finasteride is a safe and effective long-term treatment for male hair loss, especially when started early.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Sebocytes play a key role in controlling androgen levels in human skin.

Oestrogens are key for bone growth during puberty in both boys and girls.

Androgenetic alopecia in women needs more research and better management strategies.

Liposomes and niosomes improve finasteride delivery for hair loss treatment.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Finasteride effectively blocks rat enzymes, but with varying methods and strength.

Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.

Testosterone supplements can increase muscle mass and strength in older men with low levels, but long-term effects and risks need more research.

Lower SHBG levels may increase the risk of PCOS.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.