TLDR Reduced alpha smooth muscle actin may cause hair loss in androgenetic alopecia.
The study investigates the role of alpha smooth muscle actin (α-SMA) in androgenetic alopecia (AGA), a prevalent form of hair loss. It finds that α-SMA is significantly reduced in the vertex area of AGA patients, which may lead to the loss of structural integrity in hair follicles. This suggests that α-SMA plays a crucial role in the structural changes associated with AGA, highlighting the complex interplay of genetic, hormonal, and environmental factors in its development.
January 2024 in “Journal of Cosmetic Dermatology” Men's and women's pattern hair loss progress differently, with men showing more hair thinning and women having more widespread hair loss.
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January 1996 in “Springer eBooks” Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
December 2023 in “Scientific Reports” Scientists created cell lines from balding patients and found that cells from the front of the scalp are more affected by hormones that cause hair loss than those from the back.
