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This study demonstrated that a metric based on rotational echo intensity in 2H magic-angle spinning NMR can derive kinetic information for conformational exchange without complex modelling, achieving activation barriers consistent with prior findings.

Smart microneedles improve hair loss treatment by delivering drugs precisely with fewer side effects.

This study found that a novel nano-engineered platform, PCA, significantly promoted hair regeneration in an androgenetic alopecia mouse model by enhancing angiogenesis and hair follicle stem cell proliferation, showing promise for future hair regrowth treatments.

This study identified a novel missense MAFB variant in a family with some unaffected members, suggesting incomplete penetrance and the potential influence of modifier genes, epigenetic mechanisms, or environmental factors on MCTO phenotype.

This Phase II study found that BAY 43-9006, given at 400 mg orally twice daily, led to stable disease in 30% and tumor reduction in 40% of renal cell carcinoma patients.

Researchers created a new mouse model for studying scleroderma.

This study found that KSR1 is essential for v-Ha-ras-mediated skin tumor formation in mice but not for MT-driven mammary tumor genesis, suggesting its potential as a therapeutic target in Ras/MAPK signaling.

This study found that blood and milk somatic cells show promise as matrices for monitoring illicit recombinant bovine somatotropin use in dairy cattle through gene-expression assays.

This study investigated a Labrador Retriever with paw pad hyperkeratosis and identified a unique de novo heterozygous missense variant in the GJB6 gene, suggesting its potential role in the condition, analogous to Clouston syndrome in humans, although differences between species may provide further insights.

This study suggested that MRF may support skin regeneration and rejuvenation by promoting collagen synthesis and regulating factors involved in fibroblast activation and ECM remodeling, with preliminary findings indicating ADSCs might aid these processes.

This study developed a personalized microneedle that delivers finasteride directly to the skin, facilitating a sustained release and potentially reducing side effects associated with oral administration.

This study found that a commonly-used DHT enzyme immunoassay shows significant cross-reactivity with testosterone, leading to inaccurate DHT measurements compared to a gold-standard LC–MS/MS method.

This study found that the Hy-Tissue Nanofat product isolates a significant number of proliferative nucleated cells and shows potential for regenerative medicine due to its rich content of adipose-derived stem cells and pluripotent MUSE cells.

This study found that integrating machine learning enhances the predictive accuracy of forensic DNA phenotyping from low template DNA, achieving high accuracy for traits like eye color, although challenges remain for admixed populations and complex traits.

This study identifies novel subpopulations of human epidermal melanocytes and specific transcriptional programs that differ from model organisms, providing insights into melanoma dedifferentiation.

This study found genetic variations, including de novo variants and copy number variations, that may be associated with phenotypic discordance in monozygotic twins with various clinical conditions.

This study suggests that MultiDomain Peptide hydrogels may support wound healing in diabetic mice by accelerating closure and promoting tissue regeneration, though they did not inhibit bacterial growth in infected wounds as expected.

The researchers reported that epitestosterone treatment reduced eicosanoid levels generated by cyclooxygenases and lipoxygenases in rabbit liver samples with carrageenan-induced inflammation.

This study found that multiphoton microscopy effectively visualizes the microstructure of in vivo mouse skin, offering a clear view of various skin layers and components like corneocytes and collagen fibers.

This study suggests that ATR-FT-IR spectral analysis of hair fibres may detect breast cancer through increased lipid content changes linked to cancer presence.

This study introduced a simple and reliable in vitro assay capable of large-scale simultaneous screening of hair growth-promoting compounds using a 3D co-culture system of human dermal papilla and outer root sheath cells.

This study demonstrated that a light-activated RNAi approach using hollow gold nanoshells effectively targets human prostate cancer cells with reduced off-target toxicity and material use compared to standard methods.

This pilot study explored a new method using laser-capture microdissection and 16S rRNA gene sequencing to analyze the human scalp hair follicle microbiome more accurately, revealing region-specific variations in microbial diversity and abundance.

Researchers developed a quick and sensitive way to measure finasteride in blood using a small sample size.

This study analyzed dosimetric quantities in x-ray microbeam radiation therapy and found that the peak-to-valley dose ratio decreases with depth in the irradiated object.

This study found that among young women in West Bengal, India, co-occurring PCOS and related conditions like estrogen resistance and leptin receptor insufficiency are common, with notable genetic variations identified, including impairments in leptin signaling and insulin resistance.