4 citations
,
March 2023 in “IP International Journal of Comprehensive and Advanced Pharmacology” This study explored the development of a self nanoemulsifying drug delivery system to enhance the solubility and oral bioavailability of exemestane HCl for breast cancer therapy.
4 citations
,
July 2022 in “Annals of translational medicine” This study successfully developed 3D hair follicle organoids from neonatal mouse epidermal and dermal cells, showing structural and molecular resemblance to native anagen hair follicles.
3 citations
,
August 2022 in “Pharmaceuticals” This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.
2 citations
,
April 2021 in “International Journal of Molecular Sciences” This study found that the culture conditions, not species-specific differences, determined whether sika deer dermal papilla cells adopted a 3D spheroidal or 2D monolayer growth pattern, influencing their hair-inducing ability.
1 citations
,
September 2023 in “International Journal of Biological Macromolecules” This study found that a novel in-situ crosslinked self-healing hydrogel made from oxidized Bletilla striata polysaccharide and cationic gelatin enhanced wound healing and showed strong hemostatic performance in animal models, suggesting its potential as an effective wound dressing for skin trauma.
June 2022 in “Conjunctions” This article analyzes YouTube videos of men using Finasteride and Minoxidil for hair growth, suggesting these videos are a distinct self-representational genre of self-tracking with unique aesthetic characteristics.
March 2025 in “Acta Dermato Venereologica” This cross-sectional survey found that individuals with alopecia areata and androgenetic alopecia perceived stigmatization and impaired quality of life, with greater stigma reported in German-speaking participants; factors like gender, age, and disease severity influenced stigmatization levels.
4 citations
,
July 2021 in “International Journal of Environmental Research and Public Health” This study found that women with severe hair loss from childhood irradiation for tinea capitis were at a higher risk of developing psychosocial symptoms, including depression, compared to men.
3 citations
,
July 2024 in “Journal of Health Psychology” In this study, a mixed-methods survey of 357 balding men revealed that baldness is structurally stigmatized, with many participants experiencing distress and using treatments to combat it; others resisted stigma and expressed minimal distress.
May 2026 in “Acta Dermato Venereologica” This study found that 54% of alopecia areata patients attributed their condition to stress, which was linked to higher perceived personal control and significant emotional impacts.
293 citations
,
November 2011 in “Nature” This study found that the circadian clock regulates the activation state of murine epidermal stem cells, affecting tissue homeostasis and susceptibility to tumorigenesis when disrupted.
149 citations
,
July 2017 in “PLoS Biology” This study found that hair follicle patterning in development may arise from a combination of epidermal prepattern signals and mesenchymal self-organisation, with fibroblast growth factor and bone morphogenetic protein activities playing key roles.
82 citations
,
August 2006 in “Pharmacology, Biochemistry and Behavior” This review proposes focusing on relationships between neuroactive steroids and psychiatric disorder symptoms, rather than relying on traditional disorder classifications, and reports no new clinical findings.
68 citations
,
September 2018 in “International Journal of Molecular Sciences” In this study, researchers found that exposure to PM10 significantly increased inflammation and impaired collagen synthesis in human dermal fibroblasts, suggesting PM10 contributes to skin aging through these mechanisms.
24 citations
,
May 2013 in “Drug Design Development and Therapy” This pilot study found that a multimodal minoxidil microemulsion with diclofenac and tea tree oil was more effective and safer than minoxidil alone for treating androgenic alopecia over 32 weeks.
February 2021 in “International journal of men's social and community health” This study found that participants perceived bald men more negatively based on facial expressions and reported varied body dissatisfaction, which was weakly linked to wellbeing and muscularity behaviors.
57 citations
,
January 2019 in “Stem Cell Research & Therapy” OCT4 helps hair stem cells renew and fight aging, potentially aiding hair regrowth.
46 citations
,
September 2023 in “Cell Reports” This study reports that sebaceous glands can regenerate after injury through stem cell plasticity, with hair-follicle-derived stem cells replacing sebaceous gland progenitors and playing a crucial role in the regeneration process, which is dependent on FGFR2 signaling and aided by hair growth induction.
8 citations
,
May 2024 in “ACS Applied Materials & Interfaces” This study found that incorporating PCL-based nanoscaffolds into liver spheroids enhances their viability and liver-specific biofunctionality, suggesting these scaffolds improve the model's potential for preclinical drug screening by increasing sensitivity to acetaminophen toxicity compared to traditional methods.
1 citations
,
July 2025 in “Cancer Medicine” This study observed that colorectal cancer tumoroids adapted to an environment without a matrix by developing disordered self-assembly, but their tumor-specific phenotypes and drug sensitivity remained unchanged.
1 citations
,
April 2023 in “Scientific Reports” This study reported that newly developed RADA16-I peptide hybrids, with active motifs like GHK and KGHK, demonstrated improved wound healing in a mouse skin injury model without cytotoxicity, suggesting they might be effective scaffolds for tissue engineering and regeneration.
January 2024 in “Journal of Tissue Engineering” In this study, researchers developed self-assembled skin models derived from hair follicle cells, offering an ethical and reliable alternative to animal testing and bovine collagen in dermatological research by providing functional dermal and epidermal layers for substance evaluation.
December 2024 in “Stem Cell Research & Therapy” This study found that OCT4-overexpressing human hair follicle mesenchymal stem cells show promise for artificial hematopoiesis by enhancing self-renewal through cytoskeletal remodeling and the beta-catenin-dependent adherens junction pathway.
26 citations
,
September 2012 in “Cell Reports” In this study, knockout of B-raf and C-raf genes in mice showed they are not needed for early melanocyte development, but are crucial for maintaining melanocyte stem cells, as evidenced by hair graying due to stem cell depletion.
8 citations
,
September 2023 in “International Journal of Nanomedicine” In this study, researchers developed an in vitro airway-organoid model using human lung-derived cell lines on RADA16-I hydrogels to serve as a potential tool for studying adenovirus isolation, pathogenesis, and antiviral drug screening.
July 2026 in “Advanced Science” In this study, researchers found that a scallop adhesive protein (Sbp9 Δ) forms strong adhesive coatings via disulfide-sticker strategies, which also promote hair regeneration in mouse models by activating Wnt signaling and enhancing angiogenesis, proving more effective than minoxidil for androgenetic alopecia.
June 2026 in “Nature Communications” This study found that in stretch-mediated tissue expansion, fibroblasts adopt an embryonic-like, low-collagen state that enhances epidermal stem cell renewal, supporting coordinated skin expansion crucial for reconstructive surgeries.
57 citations
,
September 2006 in “Cancer Nursing” This descriptive study reported that adults undergoing chemotherapy or radiation therapy experienced severe symptoms like fatigue and constipation, with nutrition changes being a common self-care strategy.
1 citations
,
July 2024 in “New Phytologist” In this study, researchers identified that three homologous genes—ZmSPL10, ZmSPL14, and ZmSPL26—are crucial for the development of stigmatic papilla in maize, with triple knockout mutants lacking these genes showing almost no stigmatic papilla and significantly reduced kernel setting.
1 citations
,
April 2025 in “Behavioral Sciences” In a study of 435 undergraduate medical students, researchers found that rejection sensitivity was linked to increased loneliness and problematic internet use, with loneliness mediating this relationship and self-control moderating its impact, highlighting pathways and conditions that could inform interventions.