1 citations
,
June 2025 in “The Journal of Dermatology” This study demonstrated that individuals with alopecia areata in Japan experience significant stigma and mental health issues, with perceived stigma and dissatisfaction with hair growth negatively correlated with disease severity.
2 citations
,
May 2025 in “The Journal of Dermatology” This study reported that a large proportion of US adults with physician-diagnosed alopecia areata experience substantial emotional and mental health comorbidities and report significant stigma across all disease severities, yet few are receiving counseling or therapeutic intervention.
January 2025 in “Trepo - Institutional Repository of Tampere University” Alopecia areata significantly harms women's self-image, causing reduced confidence and social isolation.
8 citations
,
May 2025 in “British Journal of Dermatology” This study found that the psychosocial impact of AA is more strongly related to patients' illness perceptions and stigma than to the severity of the disease.
16 citations
,
June 2015 in “Drug Design Development and Therapy” This study found that a gelatin microparticle-containing self-microemulsifying formulation combined with Soluplus improved the oral absorption of dutasteride.
75 citations
,
June 1999 in “Pediatric Clinics of North America” This review discusses the clinical features and therapeutic goals for teenagers with PCOS, emphasizing the need for further research into its causes and potential long-term health risks, but reports no new clinical results.
62 citations
,
June 2023 in “Acta Dermato Venereologica” This observational study found that patients with various skin diseases across 17 European countries experience higher levels of perceived stigmatization than skin-healthy controls, particularly those with psoriasis, atopic dermatitis, alopecia, and bullous disorders, with factors such as disease severity and psychological distress influencing stigmatization levels.
38 citations
,
March 2021 in “JAMA Dermatology” This cross-sectional survey study found that stigmatizing attitudes toward people with alopecia are present in various social and professional settings, with stigma levels varying by alopecia severity and perceptions of its medical nature.
27 citations
,
March 2013 in “Social Semiotics” This study analyzes how commercial websites for Propecia depict male hair loss and promote medical treatment, suggesting they contribute to medicalizing a natural condition for profit.
21 citations
,
September 2016 in “Journal of Dermatological Treatment” This article proposes a new classification, the Obsessive-Compulsive Insight Continuum, to help dermatologists better understand and diagnose skin disorders with obsessive-compulsive features.
16 citations
,
November 2015 in “International Journal of Dermatology” This study found that alopecia significantly reduces quality of life among South African Black women, with subjective symptoms and self-image concerns having the greatest impact.
15 citations
,
July 2021 in “JAMA Dermatology” This study found that androgenetic alopecia is significantly associated with moderate impairment of health-related quality of life and emotions, but not with depressive symptoms.
7 citations
,
July 2018 in “Biological & Pharmaceutical Bulletin” This study found that Phyllanthus urinaria extract displayed significant anti-alopecia properties in a mouse model, showing potential as an anti-5α-reductase agent for androgenic hair loss.
January 2025 in “Dermatology Review” This paper outlines the clinical features of artefactual skin disorder, emphasizing the complexities in diagnosing the self-inflicted lesions that patients deny, and underscores the importance of integrating dermatological, psychiatric, and psychological treatment approaches.
August 2025 in “Annals of Indian Psychiatry” In a cross-sectional study, 46% of patients with androgenetic alopecia were found to have depression of borderline to moderate severity, while 62% reported no impact on their quality of life, emphasizing the need for awareness of psychiatric comorbidities among dermatologists.
January 2009 in “Springer eBooks” The document concludes that treating skin conditions should include psychological care and a multidisciplinary approach is essential for effective management.
This thesis reviews the psychological and social challenges faced by men and women with androgenetic alopecia who seek treatment, but reports no new results.
721 citations
,
October 2011 in “Nature” Different types of long-lasting stem cells are responsible for the growth and upkeep of the mammary gland.
551 citations
,
November 2013 in “Nature” This study found that differentiated airway epithelial cells can revert into functional stem cells in vivo, suggesting a more general role for this dedifferentiation process in tissue regeneration in higher vertebrates.
330 citations
,
December 2009 in “Cell stem cell” This study suggests that skin-derived precursors from Sox2(+) hair follicle dermal cells have the potential to function as dermal stem cells, supporting hair morphogenesis, dermal maintenance, and wound-healing.
91 citations
,
March 2011 in “Stem Cell Reviews and Reports” This article describes protocols for isolating and expanding human epidermal neural crest stem cells and discusses their potential for cell-based therapies in regenerative medicine, but reports no new clinical results.
49 citations
,
September 2016 in “Genes Brain & Behavior” In this study, a deficiency in the zinc finger protein Zfp462 in mice led to anxiety-like behaviors and excessive self-grooming, providing a new model for studying anxiety disorders.
45 citations
,
November 2017 in “Biomaterials” This study demonstrated a method for large-scale preparation of self-sorted hair follicle germs in vitro, which successfully generated hair follicles when transplanted into the skin of nude mice.
38 citations
,
January 2006 in “Journal of Cellular Biochemistry” This study reported the successful isolation of epithelial stem cells from mouse embryonic skin using a simple culture method, with the cells showing the potential to differentiate into multiple cell types.
30 citations
,
April 2013 in “Journal of Investigative Dermatology” This study found that ionizing radiation primarily affects keratinocyte stem cells in the hair follicle, suggesting they play a central role in radiation-induced hair graying, rather than melanocyte stem cells.
26 citations
,
January 2014 in “Cell Structure and Function” This study provides evidence that human sweat gland myoepithelial cells contain stem cells capable of self-renewal and differentiating into sweat gland luminal cells.
19 citations
,
October 2021 in “Nano letters” In an animal study, this research explored the use of a self-therapeutic nanoparticle for treating psoriasis in mice, finding that it could prevent and treat psoriatic symptoms as effectively as standard therapies without causing side effects like hair loss and skin wrinkling.
17 citations
,
August 2024 in “International Journal of Biological Macromolecules” The hydrogel dressings speed up healing and reduce scarring.
10 citations
,
November 2023 in “Frontiers in Pharmacology” In this study, researchers developed a self-assembling hydrogel called RADA-PDGF2 and found it to accelerate wound closure in a mouse model due to its pro-proliferative and pro-migratory properties, without causing cytotoxicity or immunogenicity.
10 citations
,
January 2019 in “in Vivo” In this study, finasteride was found to enhance stem cell properties in dermal papilla cells, suggesting potential benefits for hair loss management and regenerative therapies.