32 citations,
September 2018 in “Journal of pharmaceutical sciences” The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
14 citations,
May 2005 in “Farmaco” A method was created in 2005 to identify minoxidil, a hair growth ingredient, in products using two types of capillary zone electrophoresis, and it found that most products had about 2% minoxidil.
10 citations,
July 2016 in “Clinical and translational science” Sorafenib often causes mucositis, hand-foot syndrome, rash, alopecia, diarrhea, and fatigue.
3 citations,
December 2014 in “Steroids” Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.
87 citations,
March 2013 in “Expert Review of Anticancer Therapy” Afatinib often causes skin problems that need proactive management.
6 citations,
March 2018 in “Journal of Chromatography A” New method accurately measures finasteride and M3 in urine, helping evaluate pharmacokinetics.
April 2018 in “Journal of Chromatographic Science” Finasteride's stability and safety confirmed through precise analytical methods.
3 citations,
April 2021 in “Journal of Medicinal Chemistry” Finasteride may affect PNMT, causing side effects.
October 2021 in “Nepal journal of dermatology, venereology & leprology” Melatonin is good for skin health and may help treat skin conditions.
3 citations,
April 2016 in “Journal of Investigative Dermatology” Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.
9 citations,
July 2007 in “Journal of Investigative Dermatology” Claudin expression changes help the skin respond to injury.
8 citations,
May 2017 in “Singapore Medical Journal” A Korean woman with complete hair loss regrew her hair after taking tofacitinib, with no side effects.
November 1999 in “Journal of Cutaneous Medicine and Surgery” Treatments for hair loss include hormone modifiers, minoxidil, and hair transplant surgery.
4 citations,
October 2007 in “Dermatologic Clinics” Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
67 citations,
October 1997 in “Dermatologic Surgery” The EpiLight Hair Removal System removed about 60% of hair with some side effects, and more research is needed to confirm long-term effectiveness.
58 citations,
February 2016 in “Scientific reports” Blocking BACE1 and BACE2 enzymes causes hair color loss in mice.
1 citations,
June 2020 in “Journal of AOAC INTERNATIONAL” Two new methods accurately measure Aminexil, Pyridoxine, and Niacinamide in hair products.
63 citations,
April 2005 in “Mechanisms of development” Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.
September 2021 in “Journal of skin and stem cell” Lactium, a milk protein, can help reduce symptoms of skin disorders linked to stress and anxiety without side effects.
27 citations,
July 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Lasers have become precise tools in skin treatment and diagnosis, with ongoing advancements improving their effectiveness.
14 citations,
May 2012 in “Endocrine Research” The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
18 citations,
September 2021 in “Journal of Neuroendocrinology” Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
13 citations,
May 2011 in “Bioorganic & Medicinal Chemistry” Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
6 citations,
May 2022 in “Pharmaceutics” Zinc pyrithione dissolves quickly on the skin and in hair follicles, especially in smaller particles.
63 citations,
January 1992 in “Experimental Neurology” Chickens exposed to loud noise can quickly regain hearing mostly due to repair of the tectorial membrane, not just hair cell regeneration.
Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.
153 citations,
November 2004 in “Current Medicinal Chemistry” The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.
1 citations,
March 1997 in “Journal of Chromatography B: Biomedical Sciences and Applications” Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.
5 citations,
February 1997 in “Bioorganic & Medicinal Chemistry” New compounds were made that effectively block a specific enzyme related to androgen conditions.
22 citations,
January 1995 in “The American Journal of Medicine” Newer low-dose oral contraceptives with less androgenic effects improve patient compliance.