January 2023 in “Psychology” This study reported that seed germination and root hair growth were significantly enhanced after exposure to an individual whose depression was treated with Emotional Freedom Techniques, suggesting that human mood may influence seed viability.
1 citations
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December 2020 This study suggests that linoleic acid from Malva verticillata seed extracts may promote hair growth and combat androgenic alopecia by activating Wnt/β-catenin signaling and stimulating dermal papilla cell proliferation in vitro.
December 2024 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This case report describes a 62-year-old female patient with onycholysis whose condition recurred despite taking Coix seed extract, although both initial and recurrent symptoms resolved with its use, suggesting limited efficacy and warranting further study.
September 2022 in “International Journal of Science and Research (IJSR)” This study evaluated a pumpkin seed oil hair gel formulated with various additives and found that the F3 formulation had promising physicochemical properties and non-irritant characteristics for potential use in treating androgenetic alopecia.
This study found that linoleic acid from Malva verticillata seed extracts may promote hair growth and alleviate androgenic alopecia by activating the Wnt/β-catenin signaling pathway in dermal papilla cells.
6 citations
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November 2020 in “Journal of cosmetic dermatology” This study found that standardized para rubber seed oil may be a safe and effective bio-oil for stimulating hair growth and reducing hair loss, exhibiting comparable effects to minoxidil, dutasteride, and vitamin C in certain laboratory settings.
4 citations
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February 2021 in “Journal of Cosmetic Dermatology” This study found that pumpkin seed oil significantly improved hair parameters in females with pattern hair loss, demonstrating potential as a treatment comparable to minoxidil 5% foam.
12 citations
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March 2019 in “Cosmetics” In this study, a combined regimen of an oral supplement with Pinus pinaster, Grape seed extract, vitamins, and minerals, plus high SPF sunscreen, significantly improved mild-to-moderate facial melasma in 30 women over 84 days, reducing pigmentation and enhancing cosmetic appearance with no reported adverse effects.
7 citations
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January 2013 in “Journal of Cosmetics, Dermatological Sciences and Applications” This study found that incorporating Argania spinosa kernel oil and/or Theobroma grandiflorum seed butter into hair care formulations reduced protein loss in Caucasian hair dyed with an oxidative product.
9 citations
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December 2022 in “Antibiotics” This study found that coconut seed extract may effectively treat scabies in rabbits by improving infection signs and causing high mite mortality, suggesting its potential as a cost-effective herbal alternative.
January 2019 in “Journal of Dermatology and Venereology” This study reports that topical pumpkin seed oil and sesame oil were both effective in treating alopecia areata, with no significant difference in effectiveness between the two after three months.
37 citations
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January 2019 in “Dermatologic Therapy” This article is a letter to the editor discussing the treatment of telogen effluvium using a dietary supplement, but it provides no new research results.
13 citations
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February 2019 in “Journal of Microencapsulation” This study focused on designing a niosome formulation that encapsulates pumpkin seed oil for topical use, achieving high entrapment efficiency and stability over three months.
9 citations
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March 2011 in “Oxidative stress and disease” This review explores herbal medications for skin disorders, covering their clinical efficacy, safety, and common drug interactions, but reports no new clinical results.
40 citations
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August 2018 in “Skin appendage disorders” This review examines complementary and alternative medicine for alopecia and finds limited support from robust clinical trials, highlighting the need for standardized studies to evaluate efficacy and safety.
1 citations
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December 2021 in “Pakistan biomedical journal” This review explores the effectiveness of seed cycling, a modern alternative medicine approach, in treating polycystic ovary syndrome and reports no new clinical results.
August 2025 in “International Journal of Applied Pharmaceutics” This study developed a stable nanoemulsion-based hair serum containing M. oleifera seed oil, which maintained its physical characteristics and reduced the oil's sticky texture, making it more suitable for hair loss treatment compared to traditional formulations.
August 2025 in “Dermatological Reviews” This review reports that stem cell-based therapies, natural oils, and low-level laser therapy may offer promising and safe alternative treatments for alopecia, although further standardized trials are needed for confirmation.
April 2025 in “Tropical Journal of Natural Product Research” This study reports that a nanoemulsion was successfully formulated to deliver Moringa oleifera seed oil, which contains oleic acid and other fatty acids, and may serve as a promising dosage form for hair growth treatments.
December 2024 in “NATIONS UNIVERSITY INTERNATIONAL JOURNAL OF MULTI-DISCIPLINARY STUDIES” In this study, researchers reviewed non-pharmacological treatments for androgenetic alopecia, finding that substances like caffeine, rosemary oil, and saw palmetto may stimulate hair growth or inhibit dihydrotestosterone. They emphasize the need for multicenter clinical trials to further assess these natural products' efficacy in clinical practice.
3 citations
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August 2020 in “PubMed” This review discusses the absence of clinical trials on natural ingredients for managing Central Centrifugal Cicatricial Alopecia and highlights a need for more research.
This study found that nanostructured lipid carriers enabled effective follicular delivery and accumulation of anti-hair loss drugs like dutasteride in mice, suggesting potential for reduced dosage frequency.
This study concluded that a formulated herbal suspension containing selected home remedial herbs was effective for the prevention and treatment of polycystic ovary syndrome in an animal model.
2 citations
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June 2025 in “Cosmetics” This study observed that a five-week topical treatment with cold-pressed Rosa canina seed oil significantly reduced mean wrinkle scores and UV-induced spots in volunteers, suggesting potential anti-aging and photoprotective benefits attributed to its high carotenoid content.
4 citations
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January 2023 in “Medical Journal of Babylon” This clinical trial found that hemp seed oil may be a promising treatment for localized alopecia areata, with notable hair regrowth observed in some patients after eight weeks of use.
June 2025 in “Naunyn-Schmiedeberg s Archives of Pharmacology” This literature review reports that certain herbal remedies, such as rosemary, green tea, and ginseng, have shown promise in promoting hair growth and improving hair density, though variability and study design limitations highlight the need for more rigorous research.
March 2025 in “Egyptian Journal of Animal Health” This study observed that supplementing buffalo calves with a mineral mixture alone or combined with Nigella sativa seeds improved skin conditions and hematobiochemical parameters in calves suffering from parakeratosis, which is primarily due to zinc deficiency.
In this study, researchers developed and tested an herbal hair serum containing natural ingredients like banana flower extract and orange oil, which was stable and pH-balanced, with preliminary user feedback suggesting improved hair texture, reduced hair fall, and increased hair density.
November 2024 in “Clinical Cosmetic and Investigational Dermatology” This review discusses various herbal alternatives, including rosemary oil and others, for managing androgenetic alopecia but reports that more research is needed to confirm the efficacy of these natural remedies.
January 2024 in “Brazilian Journal of Hair Health” This integrative literature review suggests that phytotherapeutic products, like Saw palmetto and Green tea, could serve as viable alternatives to current medications like finasteride for treating androgenetic alopecia, potentially offering fewer side effects.