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GlossarySecondary Hair Follicles

smaller hair-producing structures that develop alongside primary follicles

Secondary hair follicles are smaller hair-producing structures that develop alongside primary hair follicles, typically in mammals with dense fur or wool. They produce finer, shorter hairs that contribute to the overall thickness and insulation properties of the animal's coat. These follicles are crucial for maintaining the density and texture of the fur, especially in species adapted to cold environments.

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Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFkB and AP-1

research Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFkB and AP-1

1 citations, February 2023 in “International Journal of Molecular Sciences”

Melatonin improves cashmere goat hair quality by increasing follicles and reducing skin aging.

research Cashmere Growth Control in Liaoning Cashmere Goat by Ovarian Carcinoma Immunoreactive Antigen-Like Protein 2 and Decorin Genes

7 citations, March 2018 in “Asian-Australasian journal of animal sciences”

OCIAD2 and DCN genes affect hair growth in goats by having opposite effects on a growth signaling pathway and inhibiting each other.

research The Morphological Basis of Vicuña Wool: Skin and Gland Structure in Vicugna Vicugna (Molina 1782)

4 citations, March 2016 in “Small ruminant research”

Vicuña wool's quality is due to a high density of fine secondary hair follicles, and their skin glands may be used for communication.

research Methionine Level in the Diet for Pregnant Female Rabbits Affects Hair Follicle Development of Baby Rabbits

January 2012

Higher methionine in pregnant rabbits' diets improves baby rabbits' hair growth.

research Seasonal Variation in Hair Follicle Activity and Fiber Growth of Both Male and Female Merghoz Goats in Western Iran

5 citations, October 2011 in “Small ruminant research”

Goat hair growth and follicle activity change with the seasons and differ between males and females.

research Androgenetic Alopecia: Mechanisms and Progression

May 2015 in “Hair transplant forum international”

Androgenetic alopecia causes hair loss by shrinking hair follicles due to androgens, with the connection between the muscle and hair follicle determining if the loss is reversible.

research Effect of Injecting Melatonin Capsules on Growth of Skin Follicles of Longdong Cashmere Goats

1 citations, January 2011 in “Journal of Animal Science and Veterinary Medicine”

Injecting melatonin improves cashmere yield by enhancing fiber growth in goats.

research Discovery of Differentially Expressed Genes in Cashmere Goat Hair Follicles by RNA Sequencing

5 citations, January 2016 in “Genetics and Molecular Research”

Researchers found 617 genes that behave differently in cashmere goat hair follicles, which could help understand hair growth.

research Histological Study of Horse Skin

February 2023 in “Mağallaẗ Tikrīt li-l-ʻulūm al-ṣirfaẗ/Tikrit journal of pure science”

Horse skin has a layered epidermis, a dermis with hair follicles, sweat and sebaceous glands, and is supplied by small arteries.

research Methionine Levels in the Diet for Pregnant Female Rabbits Affect Hair Follicle Development of Baby Rabbits

January 2012

Higher methionine levels in pregnant rabbits' diets improve hair follicle development and hair fiber diameter in their babies.

research Red LED Light Promotes Hair Follicle Development to Improve Fiber Quality in Su Line Angora Rabbit

August 2019 in “Research Square (Research Square)”

Red LED light improves the quality of Angora rabbit wool by promoting hair growth.

research In Vitro Fibre Production and Protein Deposition in Secondary Hair Follicles of the Cashmere and Angora Goat

March 1994 in “Proceedings of the British Society of Animal Production”

Angora goats produce more hair faster than Cashmere goats.

research Improved Fetal Hair Follicle Development by Maternal Supplement of Selenium at Nano Size (Nano-Se)

18 citations, September 2011 in “Livestock science”

Maternal Nano-Se supplements improve fetal hair follicle development in cashmere goats.

research Characterization and Expression Analysis of KAP7.1 and KAP8.2 Genes in Liaoning New-Breeding Cashmere Goat Hair Follicles

48 citations, February 2010 in “Molecular biology reports”

KAP7.1 and KAP8.2 genes are crucial for cashmere quality in goats.

research Effect of Nutritional Restriction on the Hair Follicles Development and Skin Transcriptome of Chinese Merino Sheep

19 citations, June 2020 in “Animals”

Poor maternal nutrition can lead to fewer wool follicles in Chinese Merino sheep.

research Genes Influencing Hair Follicle Development

2 citations, September 2017 in “Mehmet Akif Ersoy Üniversitesi Veteriner Fakültesi dergisi”

Specific genes influence hair growth and quality in goats and sheep.

Construction and Functional Analysis of CeRNA Regulatory Network Related to the Development of Secondary Hair Follicles in Inner Mongolia Cashmere Goats

research Construction and Functional Analysis of CeRNA Regulatory Network Related to the Development of Secondary Hair Follicles in Inner Mongolia Cashmere Goats

2 citations, August 2022 in “Frontiers in Veterinary Science”

The research found key RNA networks that may control hair growth in cashmere goats.

research Reduction In Wool Follicles Prior To Birth In Merino Sheep

15 citations, January 1999 in “Reproduction Fertility and Development”

Merino sheep have fewer wool follicles at birth than before birth.

research Androgenetic Alopecia: Modeling Progression and Regrowth

4 citations, April 2016 in “Experimental Dermatology”

AGA causes hair loss through follicle miniaturization and hair cycle changes; regrowth depends on anagen initiation in kenogen follicles.

research Melatonin's Effect on Hair Follicles in a Goat (Capra Hircus) Animal Model

April 2024 in “Frontiers in endocrinology (Lausanne)”

Melatonin improved secondary hair growth in goats but didn't affect primary hair density or litter size.

research Growth of Secondary Hair Follicles of the Cashmere Goat In Vitro and Their Response to Prolactin and Melatonin

56 citations, August 1994 in “PubMed”

Prolactin and melatonin can stimulate hair growth in Cashmere goat hair follicles, but melatonin may reduce follicle viability over time.

research Effect of Fasted Live-Weight Gain During the Cashmere Non-Growing Period on Cashmere Production Performance and Secondary Hair Follicle Activity of Cashmere Goats

November 2023 in “Animals”

Feeding goats more during the non-growing period increases cashmere yield and length.

research Bone Morphogenetic Protein Signaling Regulates Postnatal Hair Follicle Differentiation and Cycling

65 citations, September 2004 in “The American journal of pathology”

Blocking BMP signaling causes hair loss and disrupts hair growth cycles.

Effects of Melatonin Administration to Cashmere Goats on Cashmere Production and Hair Follicle Characteristics in Two Consecutive Cashmere Growth Cycles

research Effects of Melatonin Administration to Cashmere Goats on Cashmere Production and Hair Follicle Characteristics in Two Consecutive Cashmere Growth Cycles

8 citations, August 2020 in “Domestic Animal Endocrinology”

Melatonin improved cashmere production in goats during the first cycle but had no lasting effects on the next cycle.

research Growth and Viability of Liaoning Cashmere Goat Hair Follicles During the Annual Hair Follicle Cycle

10 citations, January 2014 in “Genetics and Molecular Research”

Liaoning Cashmere goat hair follicles show synchronized growth patterns with lowest activity in May.

research Generation of Tβ4 Knock-In Cashmere Goat Using CRISPR/Cas9

17 citations, January 2019 in “International journal of biological sciences”

Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.

research Melatonin Regulates the Periodic Growth of Cashmere by Upregulating the Expression of Wnt10b and β-Catenin in Inner Mongolia Cashmere Goats

9 citations, July 2021 in “Frontiers in genetics”

Melatonin makes cashmere grow earlier and more by increasing certain gene activity in goats.