3 citations
,
May 2016 in “Dermatopathology” The researchers reported that Lrig1 overexpression was observed in 100% of sebaceous carcinoma cases, suggesting it may serve as a potential marker for poorly differentiated sebaceous carcinoma.
7 citations
,
February 2021 in “Dermatologic Therapy” This review discusses various pathologies involving sebaceous glands, primarily and secondarily, but reports no new clinical findings.
September 2023 in “International Journal of Community Medicine and Public Health” This source reviews a range of sebaceous gland disorders, exploring their clinical characteristics, risk factors, and common treatments, including conditions such as sebaceous gland hyperplasia and acne vulgaris, and highlighting various therapeutic approaches.
3 citations
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April 2019 in “Stem cells international” This study found that CRABP1, Nestin, and Ephrin B2 are expressed in both the tumor stroma and invasive front of skin adnexal tumors and basal cell carcinomas.
March 2005 in “Journal of the American Academy of Dermatology” Recognizing minor skin lesions can help identify serious cancer syndromes.
70 citations
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August 2006 in “Cancer Research” This study found that inhibiting AP-1 activity in mice modified tumor development, leading to transdifferentiation between squamous and sebaceous tumors, with molecular analysis suggesting AP-1's role in maintaining tumor cell identity.
This study found that inhibiting AP-1 transcription factors in mice causes squamous tumors to transform into sebaceous tumors and regulates tumor cell lineage.
This study found that inhibiting AP-1 activity in mice can induce lineage transdifferentiation between squamous and sebaceous tumors, suggesting AP-1's role in maintaining tumor cell identity.
8 citations
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January 2014 in “Annals of Dermatology” This study found that TGF-β1 expression in follicular tumors correlates with differentiation degree and suggests its potential role alongside p63 in differentiating between sebaceous and follicular tumors.
5 citations
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February 2015 in “Journal of Comparative Pathology” This study suggests that high proliferative activity and peripheral invasion are key indicators of malignancy in canine sebaceous gland tumours. It also reports a higher incidence of circumanal gland and testicular tumours, indicating a possible androgen-related pathway in tumour development.
16 citations
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July 2012 in “Current pharmaceutical biotechnology” This review discusses the pathogenesis of common sebaceous gland diseases and their molecular pathways, but it reports no new clinical findings.
13 citations
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December 2020 in “Dermatologic Therapy” This review discusses the embryology, structure, and function of sebaceous glands and their involvement in skin disorders but reports no novel findings.
107 citations
,
August 2012 in “Seminars in Cell & Developmental Biology” This review discusses the role of signaling networks in sebaceous gland development and disorders, highlighting recent insights from mouse models and cell line studies, but reports no new experimental results.
21 citations
,
November 2022 in “Frontiers in immunology” This article reviews sebaceous immunobiology and highlights the complex role of sebaceous glands and sebocytes in skin barrier function and inflammation, particularly in acne pathogenesis, but reports no new results.
97 citations
,
September 2016 in “Reviews in Endocrine and Metabolic Disorders” This review summarizes recent multidisciplinary advances in sebaceous gland research and highlights potential novel therapeutic strategies for skin diseases, but it reports no new clinical results.
60 citations
,
February 2013 in “Cell reports” This study demonstrates that c-MYC overexpression in sebaceous glands affects differentiation via a regulatory axis involving the androgen receptor and p53, influencing carcinoma formation outcomes.
56 citations
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September 2013 in “Experimental Dermatology” This guide reviews the biology of sebaceous glands and their evaluation methods, emphasizing their roles beyond lipid production in skin health and disease, and reports no new research results.
November 2023 in “Curēus” In this case report, a 16-year-old African American girl with sebaceous filaments on her face was successfully treated with topical tretinoin, highlighting the importance of recognizing and treating this under-reported condition for improved appearance and quality of life.
12 citations
,
May 2001 in “British journal of dermatology/British journal of dermatology, Supplement” A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.
April 2016 in “Journal of the American Academy of Dermatology” Dermoscopy helped correctly diagnose a skin condition that was previously misidentified as a different hair loss disease.
In this case report, researchers diagnosed a 12-year-old girl with a nevus sebaceus of Jadassohn, characterized by a yellowish-pink plaque on the scalp and a genetic variant, following previous misdiagnosis as alopecia areata.
October 2023 in “Research Review” This source describes the development, structure, and types of skin appendage tumors, noting both benign and malignant forms, potential associations with syndromes, and categories based on follicular differentiation.
22 citations
,
July 2016 in “Cellular and Molecular Life Sciences” Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
60 citations
,
March 2009 in “Dermato-Endocrinology” This review highlights recent findings on the importance of signalling pathways in sebaceous gland morphogenesis and differentiation, but reports no new clinical results.
76 citations
,
November 2009 in “Medical Clinics of North America” This article reviews the hormonal and medication-related factors associated with acne development but does not present new research findings.
59 citations
,
January 2005 in “Endocrine Journal” This study found that sex steroid hormone receptors are largely maintained during the transformation of skin appendages to neoplasms, except for androgen and estrogen receptors in sweat and sebaceous gland tumors.
research Acne
2 citations
,
May 2011 in “Harper's Textbook of Pediatric Dermatology” Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.
2 citations
,
December 2004 in “Medicine” This review discusses various causes of hair loss, emphasizing the importance of a structured diagnostic approach, and reports no new clinical findings.
This chapter classifies various benign skin tumors and discusses their characteristics, treatment indications, and potential for recurrence, but reports no new clinical findings.
260 citations
,
December 2012 in “Cold Spring Harbor Perspectives in Biology” This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.