349 citations,
January 2005 in “The FASEB journal” Human skin can make serotonin and melatonin, which help protect and maintain it.
65 citations,
August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
51 citations,
January 2004 in “Skin Pharmacology and Physiology” The document explains hair growth and shedding, factors affecting it, and methods to evaluate hair loss, emphasizing the importance of skin biopsy for diagnosis.
39 citations,
August 2016 in “Journal of Dermatological Treatment” Stem cell therapy may help treat tough hair loss cases.
19 citations,
November 2018 in “Nutrients” Annurca apple extract may protect mouse hair from damage by chemotherapy and could help treat hair loss without promoting cancer growth.
18 citations,
October 2018 in “Nutrients” Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
14 citations,
July 2016 in “Anatomical Science International” The study suggests that the arrector pili muscle is important for hair health and its damage might contribute to hair loss.
5 citations,
June 2016 in “Dermatologic Surgery” Hair restoration for East Asians should consider their unique characteristics like head shape, hair thickness, and hair density, and use modified procedures and treatments to minimize scarring and maintain hair density.
4 citations,
May 2005 in “Seminars in Plastic Surgery” Carlos Oscar Uebel developed a hair transplant method that looks natural, has low risk, and shows full growth in 6-12 months.
3 citations,
August 1998 in “Dermatologic Surgery” Bobby Limmer was crucial in developing a hair transplant method that uses natural hair groupings for a more realistic look.
January 2016 in “Human & Experimental Toxicology” A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.
March 2022 in “Lasers in Medical Science” August 2023 in “Stem Cell Research & Therapy” Using adipose-derived stem cell media with minoxidil may help regrow hair in men with hair loss.
May 2023 in “Journal of Investigative Dermatology” Blocking DPP4 can potentially speed up hair growth and regeneration, especially after injury or in cases of hair loss.
February 2022 in “Chinese Journal of Dermatology” A 36-year-old woman with worsening hair loss over 10 years was treated with various medications, and after six months, her hair loss did not worsen significantly.
245 citations,
October 2015 in “Nature medicine” Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
235 citations,
July 1999 in “Journal of biological chemistry/The Journal of biological chemistry” Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.
44 citations,
January 2013 in “BMC Dermatology” TGFβ signaling prevents sebaceous gland cells from producing fats.
34 citations,
July 2020 in “American journal of human genetics” Changes in the SREBF1 gene cause a rare genetic skin and hair disorder.
24 citations,
February 2011 in “The American journal of pathology” AIRE protein, defective in APECED patients, is found in skin and hair cells and interacts with cytokeratin 17.
3 citations,
December 2022 in “Cells” Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
July 2023 in “Journal of Clinical Medicine” The document concludes that understanding hair follicle histology and the hair cycle is crucial for diagnosing alopecia.
January 2020 in “Journal of Cosmetics, Dermatological Sciences and Applications” TrichoxidilTM could be a promising new treatment for hair loss.
550 citations,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Researchers successfully isolated and identified key markers of stem cell-enriched human hair follicle bulge cells.
450 citations,
January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
286 citations,
June 2012 in “Nature Immunology” Hair follicles help attract immune cells to the skin during stress.
16 citations,
March 2021 in “Frontiers in cell and developmental biology” A new method using Y-27632 improves the growth and quality of human hair follicle stem cells for tissue engineering and therapy.
10 citations,
February 2021 in “PLoS biology” Corin helps control salt and sweat release in sweat glands.
May 2023 in “Journal of Clinical Medicine” New understanding and treatments for hair loss are improving, but more research is needed.
January 2023 in “Journal of Cosmetics, Dermatological Sciences and Applications” The hair growth serum Trichosera® was effective in increasing hair regrowth and density and reducing hair fall without significant side effects.