research The Use of Serenoa Repens (Saw Palmetto) in Hair Care Products
Saw palmetto in hair products might reduce hair loss but can cause side effects.
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research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
research Novel Inhibitors of 5α-Reductase
New research is needed to create better drugs that block the enzyme responsible for conditions like male baldness and prostate enlargement.
research Phytochemicals With Anti 5-Alpha-Reductase Activity: A Prospective For Prostate Cancer Treatment
Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.
research Estrogen and Androgen Signaling in the Pathogenesis of Benign Prostatic Hyperplasia
Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.
research Diagnosis of Hyperandrogenism: Biochemical Criteria
The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.
research Cosmeceuticals
Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.
research Kinetic Analysis of LY320236: Competitive Inhibitor of Type I and Non-Competitive Inhibitor of Type II Human Steroid 5α-Reductase
LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
research PNU 157706, A Novel Dual Type I and II 5α-Reductase Inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research Female Pattern Hair Loss
Over 50% of women over 50 experience hair loss, with minoxidil being the only proven effective treatment.
research LY191704: A Selective, Nonsteroidal Inhibitor of Human Steroid 5 Alpha-Reductase Type 1
LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.
research Alopecia: The Search for Novel Agents Continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research An Update on Hair Restoration
Hair transplantation is the best treatment for hair loss, with new technologies improving results, and stem cell and gene therapies may treat severe baldness in the future.
research Synergistic Protective Effect of Finasteride and Black Soybean Extract Against Dihydrotestosterone-Induced Damage in Human Follicle Dermal Papilla Cells
Combining finasteride and black soybean extract better protects hair cells from damage and may treat hair loss effectively with fewer side effects.
research Cyanidin 3-O-Arabinoside Suppresses DHT-Induced Dermal Papilla Cell Senescence by Modulating p38-Dependent ER-Mitochondria Contacts
Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.
research Androgenetic Alopecia in Men and Women
Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.
research Design and Evaluation of Hair Growth-Hair Fall Oil Formulation from Botanicals
The herbal hair oil increased hair growth and reduced hair fall for most users without significant side effects.
research Effect of the Multifunctional Cosmetic Ingredient Sphinganine on Hair Loss in Men and Women with Diffuse Hair Reduction
Sphinganine can reduce hair loss and improve scalp health.
research TR3 Is Preferentially Expressed by Bulge Epithelial Stem Cells in Human Hair Follicles
TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
research Mechanism of Androgenic Alopecia: Addressing Speculations Through Empirical Evidence
Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.
research Consequences of Steroid-5α-Reductase Deficiency and Inhibition in Vertebrates
Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
research Medical Management Options for Hair Loss
The document concluded that FDA-approved treatments like minoxidil and finasteride are effective for hair loss, while the effectiveness of natural remedies and other non-approved treatments is not well-supported by evidence.
research Using Platelet-Rich Plasma to Treat Hair Loss and Thinning
Platelet-rich plasma (PRP) injections effectively treat hair loss and thinning in both men and women, with high satisfaction and no major side effects.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research FCE 28260, A New 5α-Reductase Inhibitor: In Vitro and In Vivo Effects
FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research Premature Graying of Scalp Hairs Treated with Ferrous Sulfate
Iron supplements may reverse premature hair graying caused by iron deficiency.
research Topical Finasteride: A Comprehensive Review of Androgenetic Alopecia Management for Men and Women
Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.
research Relationship of Early-Onset Baldness to Prostate Cancer in African-American Men
Early-onset baldness is linked to a higher risk of aggressive prostate cancer in African-American men, especially before age 60.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.