17 citations
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May 2021 in “Journal of Cell Science” In this study, the researchers discovered that specific polyamine depletion enhances stemness in hair follicle stem cells through a mechanism independent of mRNA translation.
April 2017 in “Journal of Investigative Dermatology” This study found that retinoic acid and a retinol complex formulation showed different permeation and compound localization in a skin equivalent model, with unique lipid changes observed with only the retinol formulation.
63 citations
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November 1999 in “British journal of dermatology/British journal of dermatology, Supplement” This study observes the expression of mRNA for androgen receptor, 5α‐reductase, and 17β‐hydroxysteroid dehydrogenase in human dermal papilla cells.
20 citations
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September 1983 in “Archives of dermatology” This study observed that minimal doses of the arotinoid RO 13-6298 successfully treated two cases of severe psoriasis and psoriatic arthritis unresponsive to traditional therapies, despite some side effects.
January 2023 in “Acta medica Philippina” This study found that ethyl acetate extract of Carica papaya flowers exhibited the highest antioxidant and 5α-reductase inhibitory activities, suggesting potential hair growth-promoting properties.
February 2007 in “Journal of Clinical Dermatology”
This study identified ISPP-Rb, a novel immuno-stimulatory complex from Royoporus badius, that significantly activates murine macrophage cells and induces multiple proinflammatory cytokines.
13 citations
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January 2007 in “International journal of pharmaceutics” This study found that a papain-containing cream had a significantly greater depilatory effect and altered skin morphology more than a papain-containing gel when applied to mice.
7 citations
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March 2021 in “Molecular Medicine Reports” This study demonstrated that culturing high-passage dermal papilla cells with specific supplemented conditioned media may preserve their hair-inducing abilities, suggesting potential for reconstructing new hair follicles in vivo.
1 citations
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June 2023 in “Animals” In this study, researchers found that overexpression of CRABP2 enhanced the proliferation of dermal papilla cells in Hu sheep through activation of the Wnt/β-catenin pathway, even when the pathway was inhibited.
7 citations
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September 1991 in “Journal of Andrology” In this study, 4‐MAPC treatment reduced ventral prostate weight in rats primarily through decreased synthetic activity, with testosterone propionate increasing prostate weight and activity at pharmacologic doses.
2 citations
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June 2017 in “ScienceRise” This study developed a mask-cream containing Sabal palm extract and Sophora japonica tincture for androgenic alopecia prevention and treatment, establishing optimal production techniques using a reverse emulsion method.
July 2024 in “Journal of Investigative Dermatology”
March 2014 in “Chinese Journal of Dermatology” This study found that dermal papilla cells from different scalp regions of AGA patients showed differential gene expression related to cell proliferation, apoptosis, and signaling pathways when exposed to DHT in a 3D culture.
20 citations
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October 2005 in “Archives of Dermatological Research”
July 2007 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study introduced the BASP classification, a new system for categorizing pattern hair loss in both men and women, and applied it to analyze 2213 Korean subjects.
June 1967 in “Journal of Cellular Physiology” This study developed an in vitro 3D organoid model using dermal papilla spheroids and found that it enhances growth factor expression and extracellular matrix production, which could aid drug screening for hair regeneration.
September 2023 in “International Journal of Dermatology” In this study, FAPD was characterized in a Chinese population by perifollicular mast cell infiltration, suggesting young individuals may be at higher risk than previously thought.
In this study, researchers found that the keratin-associated protein 36-1 gene (KRTAP36-1) allele C is linked to variations in mean fibre curvature of fine wool in Chinese Tan lambs, suggesting its role in their distinctive curly coat.
20 citations
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August 2003 in “Clinical and Experimental Dermatology” In this study, a novel E583V missense mutation in the hairless gene was identified in an Italian family with atrichia with papular lesions, reinforcing the significance of zinc-finger and LXXLL domains in this condition.
9 citations
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October 2022 in “Journal of Molecular Neuroscience” This study reports a novel LSS gene mutation in an Egyptian family with alopecia intellectual disability syndrome 4, expanding the known clinical and genetic features of the condition.
January 2017 in “Seoul National University Open Repository (Seoul National University)” This study found that the N-terminal fragment of AIMP1 enhances hair growth and proliferation of hair follicle stem cells in mice, suggesting its potential as a therapeutic peptide for hair loss treatment.
September 2016 in “Journal of the Society of Cosmetic Scientists of Korea” This study found that Resina Pini and its main component, abietic acid, significantly promoted hair growth in a mouse model of androgenic alopecia by inhibiting 5α-reductase activity.
54 citations
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January 2013 in “Journal of Biological Macromolecules” This study proposes a new method to selectively isolate keratin-associated proteins and keratin from human hair, suggesting that KAPs may support keratin fibers in hair structure.
January 2009 in “China Practical Medicine” This study found that several genes, including capping protein, palladin, VEGF, and HSPC-related clones, might cooperatively influence the aggregation, proliferation, and cycle control of dermal papilla cells, potentially affecting hair follicle behavior.
November 2022 in “Nihon Nyuusankin Gakkaishi/Nihon Nyūsankin Gakkaishi” In a non-blinded study with 12 Japanese participants, applying a lotion containing Lactiplantibacillus plantarum N793 to the scalp for 24 weeks significantly increased hair density and reduced hair loss, with participants reporting improvements in hair thickness and volume, and the treatment deemed safe.
10 citations
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June 2001 in “Annals of neurology” This study reports that patients with Alzheimer's disease have increased levels of polyamines in their hair.
11 citations
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November 2019 in “The FASEB Journal” In this study, a missense mutation in the MAP2 gene was found to be associated with reduced hair follicle density, leading to the hairless phenotype in pigs.
1 citations
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January 2016 in “Case Reports in Clinical Medicine” This case report describes a 46-year-old Japanese man with syphilitic alopecia and HIV who showed rapid improvement and hair regrowth after taking ampicillin.
March 2014 in “Hair transplant forum international” This abstract discusses a collaboration between the Asian Association of Hair Restoration Surgeons and another group, but it reports no new research findings.