N1-Acetylspermidine Is a Determinant of Hair Follicle Stem Cell Fate

May 2021 in “ Journal of Cell Science ”

Kira Allmeroth, Christine S. Kim, Andrea Annibal, Andromachi Pouikli, Janis Koester, Maxime Derisbourg, Carlos Andrés Chacón‐Martínez, Christian Latza, Adam Antebi, Peter Tessarz, Sara A. Wickström, Martin S. Denzel

N1-acetylspermidine hair follicle stem cells polyamines SSAT stem cell fate self-renewal proliferation differentiation

Studysummary In this study, the researchers discovered that specific polyamine depletion enhances stemness in hair follicle stem cells through a mechanism independent of mRNA translation.

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