February 2006 in “Journal of The American Academy of Dermatology” This study found that Malassezia globosa, a scalp-associated fungus linked to dandruff, grows with saturated but not unsaturated fatty acids, potentially causing unsaturated fatty acid accumulation on the scalp and triggering dandruff-like flaking in susceptible individuals.
22 citations
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September 2020 in “Journal of the American Academy of Dermatology” This study suggests that apremilast shows prolonged efficacy for up to 2 years in hidradenitis suppurativa patients who initially responded to the treatment, although further verification in a larger cohort is needed.
42 citations
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November 2018 in “Archives of dermatological research” Apremilast was not effective in treating moderate-to-severe alopecia areata.
3 citations
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April 2016 in “Research and reports in urology” In a cell-free test setting, this study found that a novel saw palmetto extract effectively inhibited the 5α-reductase type II enzyme, showing promising bioactivity comparable to finasteride for promoting prostate health.
December 2023 in “Journal of Medicinal Chemistry” In this study, researchers identified compound 30a as a promising topical androgen receptor antagonist that promoted hair growth in mouse models of androgenetic alopecia without noticeable toxicity, suggesting its potential for treating this hair loss condition.
April 2012 in “Journal of evolution of medical and dental sciences” This report describes a rare case of papular atrichia in a 4-year-old girl, highlighting the absence of effective treatment to stimulate hair growth for this condition.
August 2005 in “The Journal of Cell Biology” This abstract provides a graphic illustrating that mice lacking the Sgk3 gene exhibit thin coats and abnormal hair, suggesting a role for Sgk3 kinase in hair follicle growth, but reports no new experimental findings.
1 citations
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January 2016 in “Journal of gastrointestinal & digestive system” The researchers reported that the SAGI PGP procedure resulted in excess weight loss of over 90% in the first year and normalized blood sugar levels without medication among diabetic patients by the first month post-operation.
January 2016 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that the IGF2 gene Apa1 A820G polymorphism is associated with an increased risk of developing PCOS in the studied population.
3 citations
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April 2023 in “Quality Assurance and Safety of Crops & Foods” This study found that oil extracted from Prinsepia utilis seeds is physicochemically stable and suitable for use in manufacturing ketoconazole soap, which met quality control standards and may provide a cost-effective alternative to expensive additives in cosmetic and pharmaceutical applications.
1 citations
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January 2017 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, the researchers found that a paste made from Elaeocarpus serratus and Psidium guajava leaves significantly reduced dandruff symptoms, with more than 40% of patients experiencing complete remission and 30% showing marked improvement, without any adverse reactions during the one-month treatment period.
April 2023 in “Journal of Investigative Dermatology” In this study, the KPAI and KP-IGA scoring systems for assessing keratosis pilaris showed excellent interrater and intrarater reliability, offering standardized measures for clinical and research use.
December 2022 in “Korean journal of medicinal crop science/Han-gug yagyong jagmul hag-hoeji” This study found that polysaccharide extracts from ginseng, green tea, shiitake, and aloe vera effectively protected human follicle dermal papilla and keratinocyte cells by promoting cell proliferation or inhibiting apoptosis, suggesting potential for these extracts as ingredients in cosmetics or pharmaceuticals to prevent hair loss.
January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
September 2021 in “CRC Press eBooks” This review discusses fibrosing alopecia in a pattern distribution and highlights diagnostic features, but reports no new clinical results; the authors emphasize the value of trichoscopy and histology in diagnosis.
November 2021 in “Research Square (Research Square)” This study found that 4-aminopyridine significantly improves skin wound healing by enhancing various cellular and molecular processes, suggesting its potential for rapid translational development in wound treatment.
May 2018 in “Endocrine Abstracts” SFRP-4 might be an early indicator of diabetes and hypertension in men with androgenic alopecia.
4 citations
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January 2008 in “Food Science and Technology Research” This study found that mature leaves of Japanese 'Saijo' persimmon have the highest ascorbic acid levels, whereas polyphenol levels were high in both mature leaves and adventitious shoots but low in young shoots.
November 2025 in “PubMed” This study identified nine pathogenic variants in the PADI3 gene, and variants in the S100A3 and TCHH genes, which may disrupt protein function and contribute to central centrifugal cicatricial alopecia.
1 citations
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January 2020 in “Seoul National University Open Repository (Seoul National University)” This study found that a phosphodiesterase 3 inhibitor promoted hair growth in human dermal papilla cells and stimulated anagen induction in mice, suggesting potential as a treatment for alopecia.
10 citations
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January 2016 in “Annals of Dermatology” This article discusses the factors contributing to acne and reports no new findings, focusing on the role of sebaceous lipids and associated processes.
2 citations
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February 2021 in “IONTech.” This study found that a 5% concentration of snail mucus shampoo was most effective in promoting hair growth in rabbits compared to lower concentrations.
22 citations
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May 2004 in “Tissue Engineering” This study found that collagen sponges with polyglycolic acid fibers support proper skin and hair follicle restructuring, suggesting potential usefulness for hair reconstitution research and clinical applications.
July 2023 in “International Journal of Molecular Sciences” In this study, Trapa bispinosa Roxb. pericarp extract demonstrated inhibitory effects on 5α-reductase activity both in vitro using LNCaP cells and in vivo in a mouse model of benign prostatic hyperplasia, suggesting its potential role in managing the condition.
37 citations
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March 1998 in “Lupus” This case report describes a patient with SLE and APLS who developed basaloid follicular hamartomas, which persisted despite aggressive treatment for SLE, although hair regrowth occurred.
January 2025 in “FASKES Jurnal Farmasi Kesehatan dan Sains” In this study, the researchers used molecular docking to identify Erythrabyssin II from Erythrina subumbrans as a potential candidate for anti-alopecia treatment, comparable to minoxidil, suggesting clinical trials are needed to evaluate its pharmacological effects.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study developed a partially automated protocol utilizing hair follicles for DNA extraction in marmosets, achieving reliable whole genome sequencing with low chimerism, offering an efficient alternative to blood for genetic studies in non-human primates.
2 citations
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September 2011 in “Revista de Ciências Farmacêuticas Básica e Aplicada” This study examined a shampoo containing chili pepper extract and biopolymer microspheres for hair loss treatment, finding that it was well tolerated by volunteers, particularly due to the exfoliation sensation.
1 citations
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December 2018 in “Talenta Conference Series Tropical Medicine (TM)” This study evaluated the antifungal activity of lemongrass oil in anti-dandruff gel shampoo formulations and found that a 10% lemongrass oil concentration was the most effective at inhibiting the growth of the dandruff-causing fungus Pityrosporum ovale.
17 citations
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May 2021 in “Journal of Cell Science” In this study, the researchers discovered that specific polyamine depletion enhances stemness in hair follicle stem cells through a mechanism independent of mRNA translation.