Fibrosing Alopecia in a Pattern Distribution

    September 2021 in “ CRC Press eBooks ”
    Mariya Miteva
    Image of study
    TLDR Fibrosing alopecia in a pattern distribution is a type of hair loss that may often be overlooked, especially in men.
    Fibrosing alopecia in a pattern distribution (FAPD) is a diffuse form of lichen planopilaris (LPP) that affects areas of typical male or female pattern hair loss, often with some asymmetry. The cause of the immunologic lichenoid inflammation and apoptosis-mediated process in affected follicles is unclear. In a multicenter retrospective review of 26 cases, 17 men and 9 women were affected, suggesting that FAPD may be underdiagnosed in men due to less concern about common baldness. FAPD can be associated with frontal fibrosing alopecia (FFA), eyebrow alopecia, limb alopecia, and facial and extrafacial red dots. Diagnosis can be missed in a clinical exam, but "pink goose bumps" in the patterned area and dispersed ill-defined areas of atrichia may suggest FAPD. Trichoscopy and histology are crucial for diagnosis, showing peripilar casts, interfollicular scale and erythema, and single hairs or groups of hairs emerging from the same ostium in the area of thinning.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 137 results

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 2 months ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 8 months ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community Turning vellus hairs into terminal hair

      in Research/Science  12 upvotes 1 month ago
      People are discussing hair loss treatments, including minoxidil, finasteride, and RU58841, to turn vellus hairs into terminal hairs. Some users also mention using antibiotics, oral minoxidil, dutasteride, DHT blockers, biotin, and natural remedies like onion juice and seeds to improve hair growth.

    Similar Research

    5 / 1000+ results