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This study found that anisotropic osmolyte solutions may improve hair follicle turnover and condition in both in vitro and in silico models, as well as in human volunteers with hair disorders.

This study suggests that the expression patterns of keratin and filaggrin indicate milia may originate from the outermost cells of the hair bulge in the outer root sheath.

In this study, LED irradiation was found to promote hORSC proliferation and stimulate the Wnt5a/β-catenin and ERK signaling pathways, suggesting a potential mechanism for hair growth.

This study found that betamethasone increased tyrosinase activity and melanin content in amelanotic melanocytes from human hair follicles, suggesting a potential mechanism for glucocorticoid treatment in vitiligo.

This study found that a high dose of epidermal growth factor induced hair loss in sheep by causing apoptosis in anagen hair and transitioning the hair cycle to catagen.

This review discusses the cell biological characteristics of the outer root sheath of normal human hair follicles and highlights some similarities and differences with trichilemmal tumors, but reports no new results.

This study found that isolated hair follicle outer root sheaths from mice can regenerate new dermal papillary structures in vitro, with stem cells and neutrophils playing key roles in the regeneration process.

This study found that keloid tissues exhibit epithelial-mesenchymal transition-related changes and alterations in gene expression, implicating these processes in the pathogenesis of keloids.

This study reports that EGF at specific concentrations promotes the proliferation and migration of hair follicle ORS cells by activating the Wnt/β-catenin signaling pathway in vitro.

This study found that human hematopoietic mesenchymal stem cells increased the viability and migration of human outer root sheath cells in an in vitro alopecia areata model, involving Wnt/β-catenin and JAK/STAT pathways.

This research found that reduced expression of SIRT1 in human scalp tissue may contribute to alopecia areata development by inducing immune-inflammatory responses in hair follicle cells, suggesting that SIRT1 plays a regulatory role in hair follicle immunity.

This study found that inhibiting the TRPV3 channel may significantly promote hair growth and suggests a potential therapeutic approach for hair loss and related skin diseases.

Minoxidil activation by hair enzymes predicts treatment success for female hair loss.

This study found that mesenchymal stem cells sourced from hair follicle outer root sheath showed higher differentiation efficiency and angiogenic potential for vascular graft applications compared to adipose-derived stem cells.

This study found that nestin-negative hair follicle stem cells can differentiate into neural stem cell-like cells, but not mature neurons, through a multi-step neuro-induction process.

In this study, researchers demonstrated that human hair follicle outer root sheath cells release ATP, serotonin, and histamine in response to mechanical stimulation, which subsequently activates surrounding sensory neurons.

This study demonstrated that autologous mesenchymal stem cells from hair follicles, when combined with a novel gelatin-based hydrogel, showed promising osteogenic potential and could offer a non-invasive alternative for bone regeneration.

This study found that extracellular vesicles from mesenchymal and outer root sheath stem cells may inhibit hair follicle stem cell apoptosis, suggesting potential therapeutic benefits for hair loss treatments.

This study suggests that particulate matter can induce inflammation in human outer root sheath cells, potentially affecting hair growth, through oxidative stress-dependent MAPK and JAK-STAT signaling pathways.

LED light helps human hair root cells grow and move by activating certain cell pathways.

In this study, treatment with human follicular keratinocyte-conditioned media improved the trichogenicity of cultured dermal cells by activating key signalling pathways, suggesting its potential use in cell therapy for hair loss.

This study observed that applying a pulling force to hair follicles led to significant compression of nuclei in certain cell layers and distinct collagen changes at different follicle depths.

MPZL3 protein affects hair growth cycles and could help manage hair loss.

This study found that anagen hair follicles can quickly regenerate after radiation damage by forming new progenitor cells outside the bulge, bypassing the need for telogen entry.