P140 Light-Emitting Diode Light Regulates the Proliferation of Human Outer Root Sheath Cells via Wnt/β-Catenin and ERK Pathway

January 2016 in “ 프로그램북(구 초록집) ”

Jung Eun Kim, Young Sup Woo, Kwan Jeong, Hoon Kang

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LED light human outer root sheath cells hORSCs Wnt/β-catenin pathway ERK pathway Wnt5a Axin2 Lef1 mRNA β-catenin protein phosphorylation of ERK c-Jun p38 red light treatment IL-6 IL-8 IGF-1 TGF-β1 VEGF mRNA human dermal papilla cells hDPCs outer root sheath cells Wnt pathway red light interleukin-6 interleukin-8 insulin-like growth factor 1 transforming growth factor beta 1 vascular endothelial growth factor dermal papilla cells

Studysummary In this study, LED irradiation was found to promote hORSC proliferation and stimulate the Wnt5a/β-catenin and ERK signaling pathways, suggesting a potential mechanism for hair growth.

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