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    Glossary Axin2

    protein regulating Wnt signaling, crucial for hair follicle development

    Axin2 is a protein that plays a crucial role in regulating the Wnt signaling pathway, which is important for cell growth and development. In the context of hair biology, Axin2 is involved in hair follicle development and regeneration, making it significant for understanding conditions like alopecia, where hair loss occurs.

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    1. Isoxazole 9 (ISX9), a small molecule targeting Axin, activates Wnt/β‐catenin signalling and promotes hair regrowth British Journal of Pharmacology · 2023 · 11 citations
    2. ISX9, a small molecule targeting Axin, activates Wnt/β-catenin signaling and promotes hair regrowth 2022
    3. Berberine promotes hair growth by targeting Axin2 and activating Wnt/β-catenin pathway Phytomedicine · 2025 · 7 citations
    4. Augmenting Endogenous Wnt Signaling Improves Skin Wound Healing PLoS ONE · 2013 · 61 citations
    5. First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours. Journal of Clinical Oncology · 2017 · 33 citations
    6. Effect of mycophenolic acid on proliferation of dermal papilla cells and induction of anagen hair follicles Clinical and experimental dermatology · 2015 · 16 citations
    7. Impact of substrate stiffness on dermal papilla aggregates in microgels Biomaterials Science · 2018 · 12 citations
    8. Tectoridin Stimulates the Activity of Human Dermal Papilla Cells and Promotes Hair Shaft Elongation in Mouse Vibrissae Hair Follicle Culture Molecules · 2022 · 7 citations
    9. Would you recognize this lesion as a gumma syphilitica? Journal of The American Academy of Dermatology · 2017
    10. Wnt/β-catenin and ERK pathway activation: The possible mechanism of various light-emitting diode light regulates the proliferation of human outer root sheath cells Journal of The American Academy of Dermatology · 2017
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