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    Glossary c-Jun

    protein regulating gene expression, affecting cell processes and hair growth

    c-Jun is a protein that plays a crucial role in regulating gene expression, which means it helps control which genes are turned on or off in a cell. It is part of the AP-1 (activator protein-1) transcription factor complex and is involved in various cellular processes, including cell proliferation, differentiation, and apoptosis. In the context of hair and alopecia, c-Jun can influence hair follicle development and cycling, potentially impacting hair growth and loss.

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    Research 10 of 1000+

    1. Roles of p38- and c-jun NH2-terminal kinase-mediated pathways in 2-methoxyestradiol-induced p53 induction and apoptosis Carcinogenesis · 2003 · 138 citations
    2. Stress-induced c-Jun-dependent Vitamin D Receptor (VDR) Activation Dissects the Non-classical VDR Pathway from the Classical VDR Activity 2007 · 31 citations
    3. Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway Drug Design Development and Therapy · 2017 · 18 citations
    4. 1493 Dynamic changes in fibroblast subpopulations drives development of radiation-induced skin fibrosis through the fra/c-jun pathway Journal of Investigative Dermatology · 2023
    5. Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway DOAJ (DOAJ: Directory of Open Access Journals) · 2017
    6. 446 Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway The Journal of Sexual Medicine · 2018
    7. sPLA2-IIA Overexpression in Mice Epidermis Depletes Hair Follicle Stem Cells and Induces Differentiation Mediated Through Enhanced JNK/c-Jun Activation Stem cells · 2016 · 9 citations
    8. JUNB affects hair follicle development and regeneration by promoting the proliferation of dermal papilla cells in goat Chemical and Biological Technologies in Agriculture · 2023 · 1 citations
    9. Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity Cancer Research · 2006 · 70 citations
    10. VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro Journal of Dermatological Science · 2013 · 35 citations
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