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Glossaryc-Jun

protein regulating gene expression, affecting cell processes and hair growth

c-Jun is a protein that plays a crucial role in regulating gene expression, which means it helps control which genes are turned on or off in a cell. It is part of the AP-1 (activator protein-1) transcription factor complex and is involved in various cellular processes, including cell proliferation, differentiation, and apoptosis. In the context of hair and alopecia, c-Jun can influence hair follicle development and cycling, potentially impacting hair growth and loss.

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community C’est terrible - at my wits end

in Female 443 upvotes 1 year ago

A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

community Nothing's working, I feel depressed, also hopeless for the first time

in Update 102 upvotes 2 years ago

A user's experience with hair loss treatments, including Finasteride, Minoxidil, Nizoral Shampoo, Rosemary Oil, Vitamin D, Biotin, Vitamin C, Zinc and Dermarolling, that have not been successful over the past 14 months. Other users gave advice on how to cope with the issue, such as exercising, changing mindset, and shaving their head.

community this community is so funny bro

in Satire 1761 upvotes 3 weeks ago

Hair loss treatments like finasteride, minoxidil, and dutasteride are discussed, with users sharing mixed experiences about effectiveness and side effects. Some users report positive results, while others express concerns about side effects, highlighting the importance of personal choice.

community (25Y) Oral minoxidil 10 months Oral fin 7 months & other things

in Progress Pictures 52 upvotes 1 year ago

A person treated their diffuse alopecia with oral minoxidil (10mg daily), oral finasteride (reduced to 0.25mg daily due to side effects), castor oil, vitamins, and ashwagandha, and plans a hair transplant in Turkey. They stopped using topical minoxidil, have seen improved hair density, but are still experiencing hair loss.

community [M23] AWESOME progress on DUT Mesotherapy until I ruined everything

in Progress Pictures 19 upvotes 3 years ago

A user shared their progress with hair loss treatment using Dutasteride Mesotherapy but mentioned they ruined their progress. Another user commented that Minoxidil caused shedding, which should regrow in three months.

community 2020-2024 journey. 1mg Finasteride daily. 5% minoxidil daily.

in Is this regrowth? 392 upvotes 3 months ago

A user shared their 4-year hair regrowth journey using 1mg finasteride daily and 5% minoxidil daily, reporting no side effects and noticeable improvement after 6 months. They also use a derma roller to help distribute the minoxidil foam.

community I regrew my hairline in 2 years. Never give up hope. No transplant involved either.

in Progress Pictures 1074 upvotes 5 months ago

A user shared their 2-year hair regrowth journey using finasteride, ketoconazole shampoo, and a diet change, without a hair transplant. Despite skepticism from others, the user insists the results are natural and encourages consistency and dietary adjustments.

community Can anyone confidently say their erections are the same on fin ?

in Chat 240 upvotes 5 months ago

The conversation discusses the impact of finasteride on sexual function, with many users reporting reduced libido and weaker erections despite continuing the treatment to prevent hair loss. Some users suggest checking hormone levels or switching to different dosages or treatments like dutasteride, while others share mixed experiences regarding the severity of side effects.

community Feeling good about one year's progress. Daily oral fin/topical min, no side effects.

in Progress Pictures 972 upvotes 8 months ago

A user shared their one-year hair regrowth progress using daily oral finasteride and topical minoxidil without side effects. Some people are impressed, asking for more details, while others suggest a hair transplant for further improvement.

community Mark Normand talks about finasteride experience

in Finasteride/Dutasteride 826 upvotes 1 year ago

The conversation is about hair loss and the use of finasteride as a treatment. Some users share their positive experiences with finasteride, while others mention side effects they have experienced.

community My dermatologist said I have female pattern hair loss, now my hair is fully grown back.

in Update 90 upvotes 1 year ago

A user with female pattern hair loss who tried minoxidil and various oils and supplements, but saw results only after taking iron tablets. The conversation also offered advice to get blood tests done to see if there are underlying issues causing the hair loss.

community 24M, thinning since 6 years. Starting my Journey gonna be using the big 4 ( 1mg Fin, 5% minoxidil, 1.5mm dermaroller, nizoral twice a week)

in Finasteride/Dutasteride 72 upvotes 2 years ago

A 24 year old who has been experiencing thinning hair for 6 years and is starting a course of treatment involving finasteride, minoxidil, dermarolling, and nizoral shampoo. Others are wishing them luck and offering advice on how to potentially recover from the condition.

community Fuck hair loss; acquire beard.

in Shaved/buzzed 933 upvotes 2 years ago

A user's transformation from an accountant to a spartan with a full beard, discussing the potential of DUPA and alopecia areata, as well as treatments like vitamins, topicals, and natural treatments for potential regrowth.

community 21 y/o M, 3 month amazing progress on min and topical fin, I want to share my success story.

in Progress Pictures 140 upvotes 3 years ago

A 21-year-old male who has been suffering from hair loss since he was 17, and has made great progress with a combination of minoxidil and finasteride topical solutions. They discussed the efficacy of microneedling for sensitive scalps as well.

community Diffuse hair loss and scalp biopsies

in Research 692 upvotes 3 months ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Fats on your Head to Stop Hair Loss?

in Research/Science 138 upvotes 9 months ago

The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

community Topical Minoxidil is a pain in the ass for diffuse thinners

in Minoxidil 95 upvotes 1 year ago

Topical minoxidil being a difficult product to apply, with users considering finasteride, RU58841, and oral minoxidil as alternative treatments for diffuse thinning hair. Other advice includes shaving the head in the first 3 months of using minoxidil and finding ways to apply it without saturating the hair.

community What 3 months without fin& min does😔

in Progress Pictures 261 upvotes 1 week ago

Stopping minoxidil and finasteride for three months caused significant hair loss. The user resumed treatment with 2.5mg oral minoxidil and 0.6mg finasteride and plans to update on progress in three months.

community Anyone else realize how many younger guys are balding?

in Chat 262 upvotes 1 month ago

Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

community FINASTRIDE and switch to DUTASTRIDE, my experience

in Progress Pictures 135 upvotes 2 months ago

The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

community The Worst Hair Loss Condition You (MAY) have: LPP

in Research/Science 43 upvotes 2 months ago

Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

community 3 months into treatment... I'm I hyper responsive?

in Is this regrowth? 1211 upvotes 3 months ago

A 26-year-old male started minoxidil treatment for male-pattern baldness and saw significant regrowth in three months. He is considering finasteride but is hesitant due to potential side effects.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001) Pt 2

in Research/Science 489 upvotes 3 months ago

Sugary beverages increase the risk of pattern hair loss in men by 57%. Treatments discussed include Minoxidil, finasteride, and RU58841.

community How is my hair loss stack looking?

in Finasteride/Dutasteride 180 upvotes 4 months ago

The user is using finasteride, dutasteride, Nizoral, biotin, RU58841, minoxidil, Pantostin/Alfatradiol, Stemoxydine, and micro needling for hair loss. They are considering adding oral minoxidil.

community (30M) 3 years Fin and 10 months min

in Progress Pictures 307 upvotes 4 months ago

A user shared their progress using 1.25g finasteride daily for 3 years and 5g oral minoxidil for 10 months, reporting positive results. They seek advice on further improving their hairline, with no significant side effects mentioned.

community hmi115 is coming. Prepare yourselves for what's coming

in Technology 106 upvotes 1 year ago

The conversation discusses HMI-115, a potential cure for hair loss. Users share mixed opinions, with some expressing skepticism and others sharing anecdotal evidence of its effectiveness, including photos of significant hair regrowth from a trial participant.

community I destroyed my scalp so you wouldn't have to: here's what happens when you quit topical minoxidil

in Minoxidil 280 upvotes 1 year ago

Quitting minoxidil can lead to significant hair loss, even in areas that were not thinning before, as hair becomes reliant on the treatment. Some users also report losing hair gains when stopping minoxidil despite taking finasteride.

community Have to post this since it’s been 1yr, 6 months on topical fin, 1 year on min. Came A LONG WAY

in Progress Pictures 378 upvotes 1 year ago

User used minoxidil 5% topical liquid, HIMS topical finasteride, derma rolling, DHT blocking shampoo, and castor oil with rosemary for hair loss treatment. They experienced significant progress and increased confidence.

community Finasteride is one of the best decisions I ever made

in Finasteride/Dutasteride 306 upvotes 1 year ago

This conversation is about the effectiveness of Finasteride and Minoxidil as treatments for hair loss, with SnooBooks5080 claiming positive results from using both medications. However, other participants in the conversation caution that there are potential side effects to be aware of when taking Finasteride and advise people to do their research before making a decision.

community 8 mos: oral (Du, Min), topical (Min, Ru, Ketoconazole), microneedling. NW7 for 7 years

in Progress Pictures 944 upvotes 1 year ago

A user's success in hair regrowth after taking oral and topical medications, such as minoxidil and dutasteride, and using microneedling. Other users shared their experiences and advice with treatments used to reverse hair loss.