Pulling Force Deforms Hair Follicle Root Sheath Nuclei and Surrounding Dermal Collagen Matrix Differently at Infundibulum, Isthmus, and Suprabulbar Regions

    April 2019 in “ Experimental Dermatology
    Simeon Johnson, Kevin Cowley, Timothy J. Hawkins, Arto Määttå
    Studysummary This study observed that applying a pulling force to hair follicles led to significant compression of nuclei in certain cell layers and distinct collagen changes at different follicle depths.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on onlinelibrary.wiley.com →
    Discuss this study in the Community →

    Research cited in this study 3

    1. Stem Cell Plasticity Enables Hair Regeneration Following Lgr5+ Cell Loss Nature Cell Biology · 2017
    2. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    3. Keratins of the Human Hair Follicle International review of cytology · 2005

    Related research 5

    1. Involucrin, But Not Filaggrin and Kdap mRNA, Expression Is Downregulated in 3-D Cultures of Intact Rat Hair Bulbs After Calcium Stimulation Folia Histochemica et Cytobiologica · 2011
    2. Pilomatricoma Can Differentiate Not Only Towards Hair Matrix and Hair Cortex, But Also Follicular Infundibulum, Outer Root Sheath and Hair Bulge Experimental Dermatology · 2009
    3. Keratinization of Outer Root Sheath Cells Is Prevented by Contact with Inner Root Sheath of Rat Hair Follicles Archives of Dermatological Research · 2008
    4. Apoptosis Coordinates With Proliferation And Differentiation During Human Hair Follicle Morphogenesis Journal of dermatological science · 2005
    5. Effects of Epidermal Growth Factor on the Morphology and Patterns of DNA Synthesis in Isolated Human Hair Follicles ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1994