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Research

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Molecular Functional Analyses Revealed Essential Roles of HSP90 and Lamin A/C in Growth, Migration, and Self-Aggregation of Dermal Papilla Cells

research Molecular functional analyses revealed essential roles of HSP90 and lamin A/C in growth, migration, and self-aggregation of dermal papilla cells

10 citations , May 2018 in “Cell death discovery”

This study found that the interaction between heat shock protein 90 and lamin A/C is crucial for the growth, migration, and self-aggregation of dermal papilla cells, suggesting a potential role in alopecia areata mechanisms.

research Heterotypic cell contacts and basal lamina morphology during hair follicle development in the mouse: a light, scanning, and electron microscopic study at the site of tissue interaction

13 citations , December 1983 in “Canadian journal of zoology”

This study found that mesenchymal cell processes from the dermal papilla contact epithelial hair matrix cells through gaps in the basal lamina during hair matrix cell differentiation in mouse vibrissa follicles.

research Basal Lamina Changes During Tissue Interactions in Hair Follicles—An In Vitro Study of Normal Dermal Papillae and Vitamin A-Induced Glandular Morphogenesis

34 citations , January 1983 in “Journal of Investigative Dermatology”

research Latín cadurcum 'female genitals' and Hesychian Greek xá8veog `hog': is there any connection between the terms?

1 citations , January 2006 in “Maia-rivista Di Letterature Classiche”

This review discusses the bioactive compounds and biological activities of Polygonum multiflorum Thunb. and highlights concerns about its hepatotoxicity, but reports no new clinical results.

research Inflammatory Skin Disease in Latin America: Treatment Challenges and Opportunities

December 2025 in “Journal of Inflammation Research”

This study highlights ongoing inequities in access and outcomes for inflammatory skin diseases in Latin America and emphasizes the need for regional registries, harmonized clinical guidelines, and policy reforms to improve equitable dermatologic care.

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Community Join

5 / 14 results

community Thoughts on Avixis Alfatradiol?

4 upvotes 4 years ago

Avixis Alfatradiol is a topical 5-alpha reductase inhibitor available in Latin America and Germany, but its effectiveness is questioned. A user reported worsened hair loss after using it and recommended finasteride instead due to its proven effectiveness and lower cost.

community Microneedling technique clarification

in Microneedling 16 upvotes 2 years ago

The conversation is about using a Dr. Pen for microneedling on a widow's peak, with advice to use a depth of 1.25mm and hold it in place for 10 seconds. The user is also using minoxidil.

community Any other treatments to still be hopeful for?

in Research/Science 20 upvotes 2 years ago

The conversation discusses the potential of new hair loss treatments, with a focus on pyrilutamide, gt20029, and topical alfatradiol, and the possibility of improving their effectiveness through methods like increased concentration and microneedling. Dutasteride is also mentioned as a stronger option.

community RU/Pyrilutamide access and purchase

3 upvotes 8 months ago

The conversation is about accessing and purchasing RU58841 or Pyrilutamide for hair loss treatment, with mentions of alternatives like Breezula. Users discuss price differences in various countries and suggest websites like rudirect.com for purchasing.

community Second shed is real guys !!!!!

in Is this regrowth? 134 upvotes 6 months ago

The conversation discusses hair shedding experienced by users on minoxidil and finasteride treatments, with some considering additional options like spironolactone and dutasteride. Many users report experiencing a second shedding phase but are advised to continue treatment as it may lead to thicker hair regrowth.

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Learn

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learn Rosemary

herb and oil with stimulant, circulatory, anti-inflammatory and antioxidant properties

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Experts

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