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St. John's wort increases finasteride metabolism, reducing its effectiveness; use caution when combining them.

Finasteride doesn't affect bone density in male rats.

PEVs effectively deliver minoxidil through skin.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Dihydrotestosterone causes p27 protein breakdown in ovarian and breast cancer cells by binding with SKP2.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Researchers developed a reliable way to measure hormones in urine, showing that a baldness treatment doesn't change hormone levels.

Scientists identified a unique type of human skin stem cell that could help with tissue repair.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Buschke-Ollendorff syndrome is a rare genetic disorder causing skin and bone changes, with some cases also showing ADHD or developmental delays.

Heavy metals like arsenic, cadmium, and lead can increase cancer risk and worsen outcomes.

Egyptian Mint effectively kills mosquito larvae and inhibits certain bacteria.

Herbs like Tea Tree Oil and Aloe Vera could be safer, more conditioning antidandruff alternatives to synthetic products.

The document reviews key historical figures and discoveries in dermatology.

JAK inhibitors help with skin conditions but need more research on dosing and safety.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Different soft tissue fillers can cause various skin reactions; biodegradable fillers are safer and non-biodegradable ones like silicone can lead to long-term problems.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Platelet-rich plasma may have some benefits in dermatology, but there's not enough evidence to widely recommend its use.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.