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Skin grafts are effective for chronic leg ulcers, especially autologous split-thickness grafts for venous ulcers, but more data is needed for diabetic ulcers.

Fluconazole is an effective antifungal medication with potential side effects and lacks official analytical methods for its determination.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

Tinea incognito in Iran commonly affects adults and mimics other skin conditions.

Plant-based ingredients are effective and safe for modern skincare products.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Herbal nano-formulations show potential for effective skin delivery but need more research.

Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.

Improved dermabrasion techniques in 1987 led to better treatment results for skin issues like acne scars.

Some herbs show promise as antiandrogenic agents.

Keratin 17 is modified by RSK1 in response to growth and stress, affecting skin growth and stress response.

COVID-19 can cause various skin problems, including reactions to protective gear and medication, with different rates reported worldwide, and more research is needed to fully understand these skin issues.

Stress can worsen skin conditions and affect mental health, so doctors should include stress management in skin treatment.

Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.

Women experience various skin issues at different life stages, requiring careful treatment and awareness.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

Elevated CO2 can lessen the negative impact of water shortage on soybean roots and affects specific genes.

The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.

The PP2A-B55α protein is essential for brain and skin development in embryos.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.

Finasteride and analogues separated using LC-MS-MS technique.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

The document concludes that validated methods are needed to ensure the quality of fluconazole drugs and that new antifungal medications are necessary due to safety and resistance concerns.

Human scalp fat stem cells showed improved cartilage-like development on a special scaffold with freeze-thaw treatment.

Finasteride worsens stress effects on sensory processes, possibly linking to anxiety/depression.

Ishige sinicola extract helps bone-building cells grow and mature, which could aid in treating osteoporosis.

A 15-year-old boy's severe scalp condition improved significantly with adalimumab and baricitinib treatment.