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GlossaryRibonucleic Acid

molecule that helps translate genetic information into proteins

Ribonucleic Acid, commonly known as RNA, is a molecule essential for various biological roles, including coding, decoding, regulation, and expression of genes. Unlike DNA, which is double-stranded, RNA is typically single-stranded and helps in the synthesis of proteins by carrying genetic information from DNA to the ribosomes, where proteins are made.

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research Induction of Vascular Endothelial Growth Factor Messenger Ribonucleic Acid Expression in Stored Micrografts by Aminoguanidine

3 citations , November 2005 in “Dermatologic Surgery”

Aminoguanidine increases a specific growth signal in stored hair grafts, which may help them survive better after being transplanted.

research Induction of Vascular Endothelial Growth Factor Messenger Ribonucleic Acid Expression in Stored Micrografts by Aminoguanidine

1 citations , November 2005 in “Dermatologic Surgery”

Aminoguanidine increases VEGF in stored hair micrografts, potentially improving their viability after transplant.

research Predominant expression of 5 alpha-reductase type 1 in pubic skin from normal subjects and hirsute patients.

11 citations , May 1996 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

research Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3

47 citations , June 2019 in “Nature Communications”

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

research Retinoic acid exerts sexually dimorphic effects on muscle energy metabolism and function

5 citations , September 2021 in “Journal of biological chemistry/The Journal of biological chemistry”

Retinoic acid affects male and female muscle energy use and function differently.

research Fetal Alcohol Syndrome: Current Status of Pathogenesis

171 citations , October 1990 in “Alcoholism/Alcoholism, clinical and experimental research”

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

research The Current Status of the Pharmaceutical Potential of Juniperus L. Metabolites

19 citations , July 2018 in “Medicines”

Juniperus plants contain compounds with potential for developing various medical treatments.

research Down-Stream molecular Responses to Volatile Signaling in Roots

February 2022

Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.

research Identification of Beta-Sitosterol and Stigmasterol as Possible Inhibitors of 5 Alpha-Reductase 1: An In-Silico Study

3 citations , January 2022 in “Precision medicine and clinical omics”

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

research Skipping of Exons by Premature Termination of Transcription and Alternative Splicing within Intron-5 of the Sheep SCF Gene: A Novel Splice Variant

6 citations , June 2012 in “PloS one”

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

research In Vivo Monitoring of Survival and Proliferation of Hair Stem Cells in a Hair Follicle Generation Animal Model

6 citations , July 2013 in “Molecular Imaging”

The technique allowed noninvasive tracking of hair stem cell survival and growth, showing potential for hair loss research.

research Dermatology, ed. 2

3 citations , May 1985 in “Journal of The American Academy of Dermatology”

The book "Dermatology" has useful content but some sections lack detail and accuracy; it's recommended for dermatologists to review before buying.

research Telogen effluvium as a clinical presentation of human immunodeficiency virus infection

5 citations , April 2002 in “The American Journal of Medicine”

Hair loss can be an early sign of HIV infection.

research Index

January 2019

research The PDGF/PDGFR pathway as a drug target

182 citations , August 2018 in “Molecular Aspects of Medicine”

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

research Skin Keratins

54 citations , January 2016 in “Methods in enzymology on CD-ROM/Methods in enzymology”

Keratins are important for skin cell health and their problems can cause diseases.

research Sex hormones modulate pathogenic processes in experimental traumatic brain injury

32 citations , February 2019 in “Journal of neurochemistry”

Sex hormones affect brain injury differently in males and females.

research Hair of the Dog: Identification of a Cis-Regulatory Module Predicted to Influence Canine Coat Composition

14 citations , April 2019 in “Genes”

Researchers found a genetic region that influences the number of coat layers in dogs.

Hair shaft mi<scp>RNA</scp>‐221 levels as a new tumor marker of malignant melanoma

research Hair shaft miRNA‐221 levels as a new tumor marker of malignant melanoma

7 citations , December 2014 in “Journal of dermatology”

Hair shaft miR-221 levels can help detect malignant melanoma.

Expression and Cellular Localization of Keratinocyte Growth Factor and Its Receptor in Human Hyperplastic Prostate Tissue<sup>1</sup>

research Expression and Cellular Localization of Keratinocyte Growth Factor and Its Receptor in Human Hyperplastic Prostate Tissue¹

4 citations , June 1998 in “The Journal of Clinical Endocrinology & Metabolism”

KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.

research Alopecia Areata Universalis Precipitated by SARS-CoV-2 Vaccine: A Case Report and Narrative Review

3 citations , August 2022 in “Curēus”

The SARS-CoV-2 vaccine may be linked to triggering autoimmune conditions like Alopecia Areata.

research Post-covid-19 hair loss syndrome

December 2023 in “Aesthetic Cosmetology and Medicine”

COVID-19 can cause hair loss, but specialists can help treat it.

Drug repositioning approach to target ‎viral and host cells in terms of COVID-19 treatment: A review of ‎in vivo experiments and clinical studies

research Drug repositioning approach to target ‎viral and host cells in terms of COVID-19 treatment: A review of ‎in vivo experiments and clinical studies

October 2022 in “Journal of experimental and clinical medicine”

Repurposing existing drugs for COVID-19 shows promise but requires more research to confirm effectiveness.

research Aesthetics in Geriatrics Using Plasma and Its Fractions in India

March 2021

Platelet-rich plasma is a promising and cost-effective treatment for hair and skin issues in older adults in India.

research Antiandrogens and Androgen Inhibitors

January 2021 in “Elsevier eBooks”

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

research Aesthetics in Geriatrics Using Plasma and Its Fractions in India

June 2020

PRP is a versatile and affordable treatment for improving appearance in the elderly, with patient needs and expectations being important.

research Saw Palmetto

February 2015

Saw palmetto is not proven to improve urinary flow, prostate size, or hair loss.

research American Academy of Dermatology

August 1986 in “Journal of The American Academy of Dermatology”

Minoxidil showed a 30% success rate for hair growth in a study, and various skin treatments were effective, but some had limitations or side effects.

research Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth

222 citations , January 2014 in “International journal of reproductive medicine”

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans

research Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans

39 citations , August 2008 in “Growth hormone & IGF research”

Raspberry ketone may help grow hair and improve skin elasticity.