Covid-19 in Lupus Nephritis

April 2021 in “ Bioscientia Medicina Journal of Biomedicine and Translational Research ”

Ramadhan Ananda Putra, Raveinal, Fauzar, Deka Viotra

systemic lupus erythematosus SLE lupus nephritis immunosuppressive drugs methylprednisolone hydroxychloroquine azithromycin oseltamivir SARS-CoV-2 RT-PCR lupus Plaquenil Zithromax Tamiflu COVID-19

TLDR Patients with lupus nephritis and COVID-19 can improve with proper treatment.

The document discussed the management of COVID-19 in patients with systemic lupus erythematosus (SLE), highlighting the increased risk of severe infection due to immunosuppressive drug use and the autoimmune nature of the disease. It presented a case of a patient with SLE, lupus nephritis, and other complications who was treated with methylprednisolone and hydroxychloroquine for SLE, and azithromycin plus oseltamivir for COVID-19. The patient showed clinical improvement and was discharged after 24 days of hospitalization with negative RT-PCR results. The document noted that hydroxychloroquine had a beneficial effect on SARS-CoV-2 in patients with SLE who took the medication regularly.

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