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Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Short-term finasteride treatment may lower some cell death factors in prostate cancer cells.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.

Vismodegib is effective for basal cell carcinoma but has severe side effects.

Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

FGF9 controls which receptors it binds to through a process where two FGF9 molecules join, and changes in FGF9 can lead to incorrect receptor activation.

Low vitamin D receptor levels found in hair loss patients; topical vitamin D treatment suggested.

EGFR inhibitors can cause yellowish skin eruptions.

A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.

Certain gene variations in the Vitamin D receptor may increase the risk of chronic hair loss.

ZD1839, a cancer drug, can cause mild skin rashes that are treatable without stopping the medication.

Mice skin has components that could help with hair growth and might be used for diabetes treatment.

Pioglitazone usually doesn't effectively treat or cure lichen planopilaris.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

Estrogen affects how vitamin A is processed in mouse skin, which may impact acne treatment, hair growth, and skin defense.

Androgenetic alopecia linked to COVID-19 severity; drugs reducing androgen receptor activation may help.

Hair loss can signal serious health issues, not just cosmetic concerns.

Blue light promotes hair growth by interacting with specific receptors in hair follicles.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

PPAR alpha may help in hair growth and could be a target for treatment.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.